Moore DJ - Search Results

1

α-Synuclein-induced dopaminergic neurodegeneration in a rat model of Parkinson's disease occurs independent of ATP13A2 (PARK9).

Daniel G, Musso A, Tsika E, Fiser A, Glauser L, Pletnikova O, Schneider BL, Moore DJ. Daniel G, et al. Among authors: moore dj. Neurobiol Dis. 2015 Jan;73:229-43. doi: 10.1016/j.nbd.2014.10.007. Epub 2014 Oct 18. Neurobiol Dis. 2015. PMID: 25461191

2

A rat model of progressive nigral neurodegeneration induced by the Parkinson's disease-associated G2019S mutation in LRRK2.

Dusonchet J, Kochubey O, Stafa K, Young SM Jr, Zufferey R, Moore DJ, Schneider BL, Aebischer P. Dusonchet J, et al. Among authors: moore dj. J Neurosci. 2011 Jan 19;31(3):907-12. doi: 10.1523/JNEUROSCI.5092-10.2011. J Neurosci. 2011. PMID: 21248115 Free PMC article.

3

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

Ramonet D, Daher JP, Lin BM, Stafa K, Kim J, Banerjee R, Westerlund M, Pletnikova O, Glauser L, Yang L, Liu Y, Swing DA, Beal MF, Troncoso JC, McCaffery JM, Jenkins NA, Copeland NG, Galter D, Thomas B, Lee MK, Dawson TM, Dawson VL, Moore DJ. Ramonet D, et al. Among authors: moore dj. PLoS One. 2011 Apr 6;6(4):e18568. doi: 10.1371/journal.pone.0018568. PLoS One. 2011. PMID: 21494637 Free PMC article.

4

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1.

Glauser L, Sonnay S, Stafa K, Moore DJ. Glauser L, et al. Among authors: moore dj. J Neurochem. 2011 Aug;118(4):636-45. doi: 10.1111/j.1471-4159.2011.07318.x. Epub 2011 Jun 6. J Neurochem. 2011. PMID: 21615408 Free article.

5

Mitochondrial dysfunction in genetic animal models of Parkinson's disease.

Trancikova A, Tsika E, Moore DJ. Trancikova A, et al. Among authors: moore dj. Antioxid Redox Signal. 2012 May 1;16(9):896-919. doi: 10.1089/ars.2011.4200. Epub 2011 Oct 4. Antioxid Redox Signal. 2012. PMID: 21848447 Free PMC article. Review.

6

PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity.

Ramonet D, Podhajska A, Stafa K, Sonnay S, Trancikova A, Tsika E, Pletnikova O, Troncoso JC, Glauser L, Moore DJ. Ramonet D, et al. Among authors: moore dj. Hum Mol Genet. 2012 Apr 15;21(8):1725-43. doi: 10.1093/hmg/ddr606. Epub 2011 Dec 20. Hum Mol Genet. 2012. PMID: 22186024 Free PMC article.

7

α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.

Fauvet B, Mbefo MK, Fares MB, Desobry C, Michael S, Ardah MT, Tsika E, Coune P, Prudent M, Lion N, Eliezer D, Moore DJ, Schneider B, Aebischer P, El-Agnaf OM, Masliah E, Lashuel HA. Fauvet B, et al. Among authors: moore dj. J Biol Chem. 2012 May 4;287(19):15345-64. doi: 10.1074/jbc.M111.318949. Epub 2012 Feb 7. J Biol Chem. 2012. PMID: 22315227 Free PMC article.

8

Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2.

Daher JP, Pletnikova O, Biskup S, Musso A, Gellhaar S, Galter D, Troncoso JC, Lee MK, Dawson TM, Dawson VL, Moore DJ. Daher JP, et al. Among authors: moore dj. Hum Mol Genet. 2012 Jun 1;21(11):2420-31. doi: 10.1093/hmg/dds057. Epub 2012 Feb 21. Hum Mol Genet. 2012. PMID: 22357653 Free PMC article.

9

GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1.

Stafa K, Trancikova A, Webber PJ, Glauser L, West AB, Moore DJ. Stafa K, et al. Among authors: moore dj. PLoS Genet. 2012;8(2):e1002526. doi: 10.1371/journal.pgen.1002526. Epub 2012 Feb 9. PLoS Genet. 2012. PMID: 22363216 Free PMC article.

10

Mechanisms of LRRK2-mediated neurodegeneration.

Tsika E, Moore DJ. Tsika E, et al. Among authors: moore dj. Curr Neurol Neurosci Rep. 2012 Jun;12(3):251-60. doi: 10.1007/s11910-012-0265-8. Curr Neurol Neurosci Rep. 2012. PMID: 22441981 Free article. Review.

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