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180 results

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Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.
Eirew P, Steif A, Khattra J, Ha G, Yap D, Farahani H, Gelmon K, Chia S, Mar C, Wan A, Laks E, Biele J, Shumansky K, Rosner J, McPherson A, Nielsen C, Roth AJ, Lefebvre C, Bashashati A, de Souza C, Siu C, Aniba R, Brimhall J, Oloumi A, Osako T, Bruna A, Sandoval JL, Algara T, Greenwood W, Leung K, Cheng H, Xue H, Wang Y, Lin D, Mungall AJ, Moore R, Zhao Y, Lorette J, Nguyen L, Huntsman D, Eaves CJ, Hansen C, Marra MA, Caldas C, Shah SP, Aparicio S. Eirew P, et al. Among authors: osako t. Nature. 2015 Feb 19;518(7539):422-6. doi: 10.1038/nature13952. Epub 2014 Nov 26. Nature. 2015. PMID: 25470049 Free PMC article.
Clonal analysis via barcoding reveals diverse growth and differentiation of transplanted mouse and human mammary stem cells.
Nguyen LV, Makarem M, Carles A, Moksa M, Kannan N, Pandoh P, Eirew P, Osako T, Kardel M, Cheung AM, Kennedy W, Tse K, Zeng T, Zhao Y, Humphries RK, Aparicio S, Eaves CJ, Hirst M. Nguyen LV, et al. Among authors: osako t. Cell Stem Cell. 2014 Feb 6;14(2):253-63. doi: 10.1016/j.stem.2013.12.011. Epub 2014 Jan 16. Cell Stem Cell. 2014. PMID: 24440600 Free article.
Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells.
Nguyen LV, Pellacani D, Lefort S, Kannan N, Osako T, Makarem M, Cox CL, Kennedy W, Beer P, Carles A, Moksa M, Bilenky M, Balani S, Babovic S, Sun I, Rosin M, Aparicio S, Hirst M, Eaves CJ. Nguyen LV, et al. Among authors: osako t. Nature. 2015 Dec 10;528(7581):267-71. doi: 10.1038/nature15742. Epub 2015 Dec 2. Nature. 2015. PMID: 26633636
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.
Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O'Neil NJ, Santos ND, Silvester J, Wei V, Garcia J, Kabeer F, Lai D, Soriano P, Banáth J, Chiu DS, Yap D, Le DD, Ye FB, Zhang A, Thu K, Soong J, Lin SC, Tsai AH, Osako T, Algara T, Saunders DN, Wong J, Xian J, Bally MB, Brenton JD, Brown GW, Shah SP, Cescon D, Mak TW, Caldas C, Stirling PC, Hieter P, Balasubramanian S, Aparicio S. Xu H, et al. Among authors: osako t. Nat Commun. 2017 Feb 17;8:14432. doi: 10.1038/ncomms14432. Nat Commun. 2017. PMID: 28211448 Free PMC article.
Assessment of a cancer genomic profile test for patients with metastatic breast cancer.
Fukada I, Mori S, Hayashi N, Hosonaga M, Yamazaki M, Wang X, Kawai S, Inagaki L, Ozaki Y, Kobayashi K, Hara F, Kobayashi T, Ueki A, Osako T, Tonooka A, Takeuchi K, Ueno T, Takano T, Ohno S, Takahashi S. Fukada I, et al. Among authors: osako t. Sci Rep. 2022 Mar 21;12(1):4813. doi: 10.1038/s41598-022-08925-3. Sci Rep. 2022. PMID: 35315838 Free PMC article.
Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.
Johmura Y, Maeda I, Suzuki N, Wu W, Goda A, Morita M, Yamaguchi K, Yamamoto M, Nagasawa S, Kojima Y, Tsugawa K, Inoue N, Miyoshi Y, Osako T, Akiyama F, Maruyama R, Inoue JI, Furukawa Y, Ohta T, Nakanishi M. Johmura Y, et al. Among authors: osako t. J Clin Invest. 2018 Dec 3;128(12):5603-5619. doi: 10.1172/JCI121679. Epub 2018 Nov 12. J Clin Invest. 2018. PMID: 30418174 Free PMC article.
180 results