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Microbiota organization is a distinct feature of proximal colorectal cancers.
Dejea CM, Wick EC, Hechenbleikner EM, White JR, Mark Welch JL, Rossetti BJ, Peterson SN, Snesrud EC, Borisy GG, Lazarev M, Stein E, Vadivelu J, Roslani AC, Malik AA, Wanyiri JW, Goh KL, Thevambiga I, Fu K, Wan F, Llosa N, Housseau F, Romans K, Wu X, McAllister FM, Wu S, Vogelstein B, Kinzler KW, Pardoll DM, Sears CL. Dejea CM, et al. Among authors: hechenbleikner em. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18321-6. doi: 10.1073/pnas.1406199111. Epub 2014 Dec 8. Proc Natl Acad Sci U S A. 2014. PMID: 25489084 Free PMC article.
Metabolism links bacterial biofilms and colon carcinogenesis.
Johnson CH, Dejea CM, Edler D, Hoang LT, Santidrian AF, Felding BH, Ivanisevic J, Cho K, Wick EC, Hechenbleikner EM, Uritboonthai W, Goetz L, Casero RA Jr, Pardoll DM, White JR, Patti GJ, Sears CL, Siuzdak G. Johnson CH, et al. Among authors: hechenbleikner em. Cell Metab. 2015 Jun 2;21(6):891-7. doi: 10.1016/j.cmet.2015.04.011. Epub 2015 May 7. Cell Metab. 2015. PMID: 25959674 Free PMC article. Clinical Trial.
Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria.
Dejea CM, Fathi P, Craig JM, Boleij A, Taddese R, Geis AL, Wu X, DeStefano Shields CE, Hechenbleikner EM, Huso DL, Anders RA, Giardiello FM, Wick EC, Wang H, Wu S, Pardoll DM, Housseau F, Sears CL. Dejea CM, et al. Among authors: hechenbleikner em. Science. 2018 Feb 2;359(6375):592-597. doi: 10.1126/science.aah3648. Epub 2018 Feb 1. Science. 2018. PMID: 29420293 Free PMC article.
Surgical readmissions: a method to the madness.
Hechenbleikner EM, Wick EC. Hechenbleikner EM, et al. JAMA Surg. 2014 Apr;149(4):354-5. doi: 10.1001/jamasurg.2013.4079. JAMA Surg. 2014. PMID: 24522635 No abstract available.
The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints.
Llosa NJ, Cruise M, Tam A, Wicks EC, Hechenbleikner EM, Taube JM, Blosser RL, Fan H, Wang H, Luber BS, Zhang M, Papadopoulos N, Kinzler KW, Vogelstein B, Sears CL, Anders RA, Pardoll DM, Housseau F. Llosa NJ, et al. Among authors: hechenbleikner em. Cancer Discov. 2015 Jan;5(1):43-51. doi: 10.1158/2159-8290.CD-14-0863. Epub 2014 Oct 30. Cancer Discov. 2015. PMID: 25358689 Free PMC article.
Hospital readmission by method of data collection.
Hechenbleikner EM, Makary MA, Samarov DV, Bennett JL, Gearhart SL, Efron JE, Wick EC. Hechenbleikner EM, et al. J Am Coll Surg. 2013 Jun;216(6):1150-8. doi: 10.1016/j.jamcollsurg.2013.01.057. Epub 2013 Apr 11. J Am Coll Surg. 2013. PMID: 23583617
29 results