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Peripancreatic fat necrosis worsens acute pancreatitis independent of pancreatic necrosis via unsaturated fatty acids increased in human pancreatic necrosis collections.
Gut. 2016 Jan;65(1):100-11. doi: 10.1136/gutjnl-2014-308043. Epub 2014 Dec 10.
Gut. 2016.
PMID: 25500204
Free PMC article.
Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity.
Navina S, Acharya C, DeLany JP, Orlichenko LS, Baty CJ, Shiva SS, Durgampudi C, Karlsson JM, Lee K, Bae KT, Furlan A, Behari J, Liu S, McHale T, Nichols L, Papachristou GI, Yadav D, Singh VP.
Navina S, et al. Among authors: durgampudi c.
Sci Transl Med. 2011 Nov 2;3(107):107ra110. doi: 10.1126/scitranslmed.3002573.
Sci Transl Med. 2011.
PMID: 22049070
Free PMC article.
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Acute lipotoxicity regulates severity of biliary acute pancreatitis without affecting its initiation.
Durgampudi C, Noel P, Patel K, Cline R, Trivedi RN, DeLany JP, Yadav D, Papachristou GI, Lee K, Acharya C, Jaligama D, Navina S, Murad F, Singh VP.
Durgampudi C, et al.
Am J Pathol. 2014 Jun;184(6):1773-84. doi: 10.1016/j.ajpath.2014.02.015.
Am J Pathol. 2014.
PMID: 24854864
Free PMC article.
Clinical Trial.
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Lipolysis of visceral adipocyte triglyceride by pancreatic lipases converts mild acute pancreatitis to severe pancreatitis independent of necrosis and inflammation.
Patel K, Trivedi RN, Durgampudi C, Noel P, Cline RA, DeLany JP, Navina S, Singh VP.
Patel K, et al. Among authors: durgampudi c.
Am J Pathol. 2015 Mar;185(3):808-19. doi: 10.1016/j.ajpath.2014.11.019. Epub 2015 Jan 8.
Am J Pathol. 2015.
PMID: 25579844
Free PMC article.
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Fatty Acid Ethyl Esters Are Less Toxic Than Their Parent Fatty Acids Generated during Acute Pancreatitis.
Patel K, Durgampudi C, Noel P, Trivedi RN, de Oliveira C, Singh VP.
Patel K, et al. Among authors: durgampudi c.
Am J Pathol. 2016 Apr;186(4):874-84. doi: 10.1016/j.ajpath.2015.11.022. Epub 2016 Feb 12.
Am J Pathol. 2016.
PMID: 26878214
Free PMC article.
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Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium.
Mishra V, Cline R, Noel P, Karlsson J, Baty CJ, Orlichenko L, Patel K, Trivedi RN, Husain SZ, Acharya C, Durgampudi C, Stolz DB, Navina S, Singh VP.
Mishra V, et al. Among authors: durgampudi c.
PLoS One. 2013 Jun 18;8(6):e66471. doi: 10.1371/journal.pone.0066471. Print 2013.
PLoS One. 2013.
PMID: 23824669
Free PMC article.
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Hypothermia slows sequential and parallel steps initiated during caerulein pancreatitis.
Mishra V, Patel K, Trivedi RN, Noel P, Durgampudi C, Acharya C, Holmes JA, Narla S, Singh VP.
Mishra V, et al. Among authors: durgampudi c.
Pancreatology. 2014 Nov-Dec;14(6):459-64. doi: 10.1016/j.pan.2014.06.006. Epub 2014 Jul 3.
Pancreatology. 2014.
PMID: 25459565
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