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Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis.
Gaiha GD, McKim KJ, Woods M, Pertel T, Rohrbach J, Barteneva N, Chin CR, Liu D, Soghoian DZ, Cesa K, Wilton S, Waring MT, Chicoine A, Doering T, Wherry EJ, Kaufmann DE, Lichterfeld M, Brass AL, Walker BD. Gaiha GD, et al. Among authors: soghoian dz. Immunity. 2014 Dec 18;41(6):1001-12. doi: 10.1016/j.immuni.2014.12.011. Epub 2014 Dec 8. Immunity. 2014. PMID: 25526311 Free PMC article.
HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome.
Soghoian DZ, Jessen H, Flanders M, Sierra-Davidson K, Cutler S, Pertel T, Ranasinghe S, Lindqvist M, Davis I, Lane K, Rychert J, Rosenberg ES, Piechocka-Trocha A, Brass AL, Brenchley JM, Walker BD, Streeck H. Soghoian DZ, et al. Sci Transl Med. 2012 Feb 29;4(123):123ra25. doi: 10.1126/scitranslmed.3003165. Sci Transl Med. 2012. PMID: 22378925 Free PMC article.
HIV control is mediated in part by CD8+ T-cell targeting of specific epitopes.
Pereyra F, Heckerman D, Carlson JM, Kadie C, Soghoian DZ, Karel D, Goldenthal A, Davis OB, DeZiel CE, Lin T, Peng J, Piechocka A, Carrington M, Walker BD. Pereyra F, et al. Among authors: soghoian dz. J Virol. 2014 Nov;88(22):12937-48. doi: 10.1128/JVI.01004-14. Epub 2014 Aug 27. J Virol. 2014. PMID: 25165115 Free PMC article.
Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.
Ranasinghe S, Lamothe PA, Soghoian DZ, Kazer SW, Cole MB, Shalek AK, Yosef N, Jones RB, Donaghey F, Nwonu C, Jani P, Clayton GM, Crawford F, White J, Montoya A, Power K, Allen TM, Streeck H, Kaufmann DE, Picker LJ, Kappler JW, Walker BD. Ranasinghe S, et al. Among authors: soghoian dz. Immunity. 2016 Oct 18;45(4):917-930. doi: 10.1016/j.immuni.2016.09.015. Immunity. 2016. PMID: 27760342 Free PMC article.
HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function.
Chevalier MF, Jülg B, Pyo A, Flanders M, Ranasinghe S, Soghoian DZ, Kwon DS, Rychert J, Lian J, Muller MI, Cutler S, McAndrew E, Jessen H, Pereyra F, Rosenberg ES, Altfeld M, Walker BD, Streeck H. Chevalier MF, et al. Among authors: soghoian dz. J Virol. 2011 Jan;85(2):733-41. doi: 10.1128/JVI.02030-10. Epub 2010 Nov 3. J Virol. 2011. PMID: 21047960 Free PMC article.
Association of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune control.
Ranasinghe S, Cutler S, Davis I, Lu R, Soghoian DZ, Qi Y, Sidney J, Kranias G, Flanders MD, Lindqvist M, Kuhl B, Alter G, Deeks SG, Walker BD, Gao X, Sette A, Carrington M, Streeck H. Ranasinghe S, et al. Among authors: soghoian dz. Nat Med. 2013 Jul;19(7):930-3. doi: 10.1038/nm.3229. Epub 2013 Jun 23. Nat Med. 2013. PMID: 23793098 Free PMC article.
Induction of Gag-specific CD4 T cell responses during acute HIV infection is associated with improved viral control.
Schieffer M, Jessen HK, Oster AF, Pissani F, Soghoian DZ, Lu R, Jessen AB, Zedlack C, Schultz BT, Davis I, Ranasinghe S, Rosenberg ES, Alter G, Schumann RR, Streeck H. Schieffer M, et al. Among authors: soghoian dz. J Virol. 2014 Jul;88(13):7357-66. doi: 10.1128/JVI.00728-14. Epub 2014 Apr 16. J Virol. 2014. PMID: 24741089 Free PMC article.
14 results