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Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control.
Klein DK, Hoffmann S, Ahlskog JK, O'Hanlon K, Quaas M, Larsen BD, Rolland B, Rösner HI, Walter D, Kousholt AN, Menzel T, Lees M, Johansen JV, Rappsilber J, Engeland K, Sørensen CS. Klein DK, et al. Among authors: hoffmann s. Nat Commun. 2015 Jan 5;6:5800. doi: 10.1038/ncomms6800. Nat Commun. 2015. PMID: 25557911 Free article.
VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates.
Mirsanaye AS, Hoffmann S, Weisser M, Mund A, Lopez Mendez B, Typas D, van den Boom J, Benedict B, Hendriks IA, Nielsen ML, Meyer H, Duxin JP, Montoya G, Mailand N. Mirsanaye AS, et al. Among authors: hoffmann s. Nat Commun. 2024 Mar 19;15(1):2459. doi: 10.1038/s41467-024-46760-4. Nat Commun. 2024. PMID: 38503733 Free PMC article.
Activation of the ATR kinase by the RPA-binding protein ETAA1.
Haahr P, Hoffmann S, Tollenaere MA, Ho T, Toledo LI, Mann M, Bekker-Jensen S, Räschle M, Mailand N. Haahr P, et al. Among authors: hoffmann s. Nat Cell Biol. 2016 Nov;18(11):1196-1207. doi: 10.1038/ncb3422. Epub 2016 Oct 10. Nat Cell Biol. 2016. PMID: 27723717
The ubiquitin ligase RFWD3 is required for translesion DNA synthesis.
Gallina I, Hendriks IA, Hoffmann S, Larsen NB, Johansen J, Colding-Christensen CS, Schubert L, Sellés-Baiget S, Fábián Z, Kühbacher U, Gao AO, Räschle M, Rasmussen S, Nielsen ML, Mailand N, Duxin JP. Gallina I, et al. Among authors: hoffmann s. Mol Cell. 2021 Feb 4;81(3):442-458.e9. doi: 10.1016/j.molcel.2020.11.029. Epub 2020 Dec 14. Mol Cell. 2021. PMID: 33321094 Free PMC article.
Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation.
Liu JCY, Ackermann L, Hoffmann S, Gál Z, Hendriks IA, Jain C, Morlot L, Tatham MH, McLelland GL, Hay RT, Nielsen ML, Brummelkamp T, Haahr P, Mailand N. Liu JCY, et al. Among authors: hoffmann s. Nat Struct Mol Biol. 2024 Apr 22. doi: 10.1038/s41594-024-01294-7. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38649616
1,749 results