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Page 1
Small deletion in C9orf72 hides a proportion of expansion carriers in FTLD.
Rollinson S, Bennion Callister J, Young K, Ryan SJ, Druyeh R, Rohrer JD, Snowden J, Richardson A, Jones M, Harris J, Davidson Y, Robinson A, Ealing J, Johnson JO, Traynor B, Mead S, Mann D, Pickering-Brown SM. Rollinson S, et al. Among authors: druyeh r. Neurobiol Aging. 2015 Mar;36(3):1601.e1-5. doi: 10.1016/j.neurobiolaging.2014.12.009. Epub 2014 Dec 12. Neurobiol Aging. 2015. PMID: 25595499 Free PMC article.
The TMEM106B risk allele is associated with lower cortical volumes in a clinically diagnosed frontotemporal dementia cohort.
Harding SR, Bocchetta M, Gordon E, Cash DM, Cardoso MJ, Druyeh R, Ourselin S, Warren JD, Mead S, Rohrer JD. Harding SR, et al. Among authors: druyeh r. J Neurol Neurosurg Psychiatry. 2017 Nov;88(11):997-998. doi: 10.1136/jnnp-2017-315641. Epub 2017 Apr 26. J Neurol Neurosurg Psychiatry. 2017. PMID: 28446602 Free PMC article. No abstract available.
Serum neurofilament light chain protein is a measure of disease intensity in frontotemporal dementia.
Rohrer JD, Woollacott IO, Dick KM, Brotherhood E, Gordon E, Fellows A, Toombs J, Druyeh R, Cardoso MJ, Ourselin S, Nicholas JM, Norgren N, Mead S, Andreasson U, Blennow K, Schott JM, Fox NC, Warren JD, Zetterberg H. Rohrer JD, et al. Among authors: druyeh r. Neurology. 2016 Sep 27;87(13):1329-36. doi: 10.1212/WNL.0000000000003154. Epub 2016 Aug 31. Neurology. 2016. PMID: 27581216 Free PMC article.
R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia.
Slattery CF, Beck JA, Harper L, Adamson G, Abdi Z, Uphill J, Campbell T, Druyeh R, Mahoney CJ, Rohrer JD, Kenny J, Lowe J, Leung KK, Barnes J, Clegg SL, Blair M, Nicholas JM, Guerreiro RJ, Rowe JB, Ponto C, Zerr I, Kretzschmar H, Gambetti P, Crutch SJ, Warren JD, Rossor MN, Fox NC, Collinge J, Schott JM, Mead S. Slattery CF, et al. Among authors: druyeh r. Alzheimers Dement. 2014 Nov;10(6):602-608.e4. doi: 10.1016/j.jalz.2014.05.1751. Epub 2014 Aug 23. Alzheimers Dement. 2014. PMID: 25160042 Free PMC article.
ApoE4 lowers age at onset in patients with frontotemporal dementia and tauopathy independent of amyloid-β copathology.
Koriath C, Lashley T, Taylor W, Druyeh R, Dimitriadis A, Denning N, Williams J, Warren JD, Fox NC, Schott JM, Rowe JB, Collinge J, Rohrer JD, Mead S. Koriath C, et al. Among authors: druyeh r. Alzheimers Dement (Amst). 2019 Mar 19;11:277-280. doi: 10.1016/j.dadm.2019.01.010. eCollection 2019 Dec. Alzheimers Dement (Amst). 2019. PMID: 30949567 Free PMC article.
Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases.
Thompson AGB, Anastasiadis P, Druyeh R, Whitworth I, Nayak A, Nihat A, Mok TH, Rudge P, Wadsworth JDF, Rohrer J, Schott JM, Heslegrave A, Zetterberg H, Collinge J, Jackson GS, Mead S. Thompson AGB, et al. Among authors: druyeh r. Mol Psychiatry. 2021 Oct;26(10):5955-5966. doi: 10.1038/s41380-021-01045-w. Epub 2021 Mar 5. Mol Psychiatry. 2021. PMID: 33674752 Free PMC article.
Predictors for a dementia gene mutation based on gene-panel next-generation sequencing of a large dementia referral series.
Koriath C, Kenny J, Adamson G, Druyeh R, Taylor W, Beck J, Quinn L, Mok TH, Dimitriadis A, Norsworthy P, Bass N, Carter J, Walker Z, Kipps C, Coulthard E, Polke JM, Bernal-Quiros M, Denning N, Thomas R, Raybould R, Williams J, Mummery CJ, Wild EJ, Houlden H, Tabrizi SJ, Rossor MN, Hummerich H, Warren JD, Rowe JB, Rohrer JD, Schott JM, Fox NC, Collinge J, Mead S. Koriath C, et al. Among authors: druyeh r. Mol Psychiatry. 2020 Dec;25(12):3399-3412. doi: 10.1038/s41380-018-0224-0. Epub 2018 Oct 2. Mol Psychiatry. 2020. PMID: 30279455 Free PMC article.
Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration.
Weston PSJ, Poole T, Ryan NS, Nair A, Liang Y, Macpherson K, Druyeh R, Malone IB, Ahsan RL, Pemberton H, Klimova J, Mead S, Blennow K, Rossor MN, Schott JM, Zetterberg H, Fox NC. Weston PSJ, et al. Among authors: druyeh r. Neurology. 2017 Nov 21;89(21):2167-2175. doi: 10.1212/WNL.0000000000004667. Epub 2017 Oct 25. Neurology. 2017. PMID: 29070659 Free PMC article.
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