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Genetic targeting of sprouting angiogenesis using Apln-CreER.
Liu Q, Hu T, He L, Huang X, Tian X, Zhang H, He L, Pu W, Zhang L, Sun H, Fang J, Yu Y, Duan S, Hu C, Hui L, Zhang H, Quertermous T, Xu Q, Red-Horse K, Wythe JD, Zhou B. Liu Q, et al. Among authors: wythe jd. Nat Commun. 2015 Jan 19;6:6020. doi: 10.1038/ncomms7020. Nat Commun. 2015. PMID: 25597280 Free PMC article.
Smooth muscle origin of postnatal 2nd CVP is pre-determined in early embryo.
Liu Q, Zhang H, Tian X, He L, Huang X, Tan Z, Yan Y, Evans SM, Wythe JD, Zhou B. Liu Q, et al. Among authors: wythe jd. Biochem Biophys Res Commun. 2016 Mar 18;471(4):430-6. doi: 10.1016/j.bbrc.2016.02.062. Epub 2016 Feb 18. Biochem Biophys Res Commun. 2016. PMID: 26902114 Free PMC article.
Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung.
Vila Ellis L, Cain MP, Hutchison V, Flodby P, Crandall ED, Borok Z, Zhou B, Ostrin EJ, Wythe JD, Chen J. Vila Ellis L, et al. Among authors: wythe jd. Dev Cell. 2020 Mar 9;52(5):617-630.e6. doi: 10.1016/j.devcel.2020.01.009. Epub 2020 Feb 13. Dev Cell. 2020. PMID: 32059772 Free PMC article.
Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease.
Rohde D, Vandoorne K, Lee IH, Grune J, Zhang S, McAlpine CS, Schloss MJ, Nayar R, Courties G, Frodermann V, Wojtkiewicz G, Honold L, Chen Q, Schmidt S, Iwamoto Y, Sun Y, Cremer S, Hoyer FF, Iborra-Egea O, Muñoz-Guijosa C, Ji F, Zhou B, Adams RH, Wythe JD, Hidalgo J, Watanabe H, Jung Y, van der Laan AM, Piek JJ, Kfoury Y, Désogère PA, Vinegoni C, Dutta P, Sadreyev RI, Caravan P, Bayes-Genis A, Libby P, Scadden DT, Lin CP, Naxerova K, Swirski FK, Nahrendorf M. Rohde D, et al. Among authors: wythe jd. Nat Cardiovasc Res. 2022 Jan;1(1):28-44. doi: 10.1038/s44161-021-00002-8. Epub 2021 Dec 23. Nat Cardiovasc Res. 2022. PMID: 35747128 Free PMC article.
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY. Jones CA, et al. Among authors: wythe jd. Nat Med. 2008 Apr;14(4):448-53. doi: 10.1038/nm1742. Epub 2008 Mar 16. Nat Med. 2008. PMID: 18345009 Free PMC article.
Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network.
Fish JE, Cantu Gutierrez M, Dang LT, Khyzha N, Chen Z, Veitch S, Cheng HS, Khor M, Antounians L, Njock MS, Boudreau E, Herman AM, Rhyner AM, Ruiz OE, Eisenhoffer GT, Medina-Rivera A, Wilson MD, Wythe JD. Fish JE, et al. Among authors: wythe jd. Development. 2017 Jul 1;144(13):2428-2444. doi: 10.1242/dev.146050. Epub 2017 May 23. Development. 2017. PMID: 28536097 Free PMC article.
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