Weiser BP - Search Results

1

Discovery of a novel general anesthetic chemotype using high-throughput screening.

McKinstry-Wu AR, Bu W, Rai G, Lea WA, Weiser BP, Liang DF, Simeonov A, Jadhav A, Maloney DJ, Eckenhoff RG. McKinstry-Wu AR, et al. Among authors: weiser bp. Anesthesiology. 2015 Feb;122(2):325-33. doi: 10.1097/ALN.0000000000000505. Anesthesiology. 2015. PMID: 25603205 Free PMC article.

2

Mechanisms revealed through general anesthetic photolabeling.

Weiser BP, Woll KA, Dailey WP, Eckenhoff RG. Weiser BP, et al. Curr Anesthesiol Rep. 2014 Mar 1;4(1):57-66. doi: 10.1007/s40140-013-0040-7. Curr Anesthesiol Rep. 2014. PMID: 24563623 Free PMC article.

3

In vivo activation of azipropofol prolongs anesthesia and reveals synaptic targets.

Weiser BP, Kelz MB, Eckenhoff RG. Weiser BP, et al. J Biol Chem. 2013 Jan 11;288(2):1279-85. doi: 10.1074/jbc.M112.413989. Epub 2012 Nov 26. J Biol Chem. 2013. PMID: 23184948 Free PMC article.

4

Sites and functional consequence of VDAC-alkylphenol anesthetic interactions.

Weiser BP, Bu W, Wong D, Eckenhoff RG. Weiser BP, et al. FEBS Lett. 2014 Nov 28;588(23):4398-403. doi: 10.1016/j.febslet.2014.10.009. Epub 2014 Oct 18. FEBS Lett. 2014. PMID: 25448677 Free PMC article.

5

Propofol inhibits SIRT2 deacetylase through a conformation-specific, allosteric site.

Weiser BP, Eckenhoff RG. Weiser BP, et al. J Biol Chem. 2015 Mar 27;290(13):8559-68. doi: 10.1074/jbc.M114.620732. Epub 2015 Feb 9. J Biol Chem. 2015. PMID: 25666612 Free PMC article.

6

Role for the propofol hydroxyl in anesthetic protein target molecular recognition.

Woll KA, Weiser BP, Liang Q, Meng T, McKinstry-Wu A, Pinch B, Dailey WP, Gao WD, Covarrubias M, Eckenhoff RG. Woll KA, et al. Among authors: weiser bp. ACS Chem Neurosci. 2015 Jun 17;6(6):927-35. doi: 10.1021/acschemneuro.5b00078. Epub 2015 Mar 30. ACS Chem Neurosci. 2015. PMID: 25799399 Free PMC article.

7

Direct modulation of microtubule stability contributes to anthracene general anesthesia.

Emerson DJ, Weiser BP, Psonis J, Liao Z, Taratula O, Fiamengo A, Wang X, Sugasawa K, Smith AB 3rd, Eckenhoff RG, Dmochowski IJ. Emerson DJ, et al. Among authors: weiser bp. J Am Chem Soc. 2013 Apr 10;135(14):5389-98. doi: 10.1021/ja311171u. Epub 2013 Mar 29. J Am Chem Soc. 2013. PMID: 23484901 Free PMC article.

8

Macroscopic and macromolecular specificity of alkylphenol anesthetics for neuronal substrates.

Weiser BP, Hall MA, Weinbren NL, Woll KA, Dailey WP, Eckenhoff MF, Eckenhoff RG. Weiser BP, et al. Sci Rep. 2015 Apr 8;5:9695. doi: 10.1038/srep09695. Sci Rep. 2015. PMID: 25853337 Free PMC article.

9

Computational investigation of cholesterol binding sites on mitochondrial VDAC.

Weiser BP, Salari R, Eckenhoff RG, Brannigan G. Weiser BP, et al. J Phys Chem B. 2014 Aug 21;118(33):9852-60. doi: 10.1021/jp504516a. Epub 2014 Aug 11. J Phys Chem B. 2014. PMID: 25080204 Free PMC article.

10

High-Throughput Screening Identifies Ascorbyl Palmitate as a SIRT2 Deacetylase and Defatty-Acylase Inhibitor.

Hong JY, Cassel J, Yang J, Lin H, Weiser BP. Hong JY, et al. Among authors: weiser bp. ChemMedChem. 2021 Nov 19;16(22):3484-3494. doi: 10.1002/cmdc.202100343. Epub 2021 Sep 2. ChemMedChem. 2021. PMID: 34382754

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