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A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment.
Steiling K, van den Berge M, Hijazi K, Florido R, Campbell J, Liu G, Xiao J, Zhang X, Duclos G, Drizik E, Si H, Perdomo C, Dumont C, Coxson HO, Alekseyev YO, Sin D, Pare P, Hogg JC, McWilliams A, Hiemstra PS, Sterk PJ, Timens W, Chang JT, Sebastiani P, O'Connor GT, Bild AH, Postma DS, Lam S, Spira A, Lenburg ME. Steiling K, et al. Among authors: postma ds. Am J Respir Crit Care Med. 2013 May 1;187(9):933-42. doi: 10.1164/rccm.201208-1449OC. Am J Respir Crit Care Med. 2013. PMID: 23471465 Free PMC article.
Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity.
van den Berge M, Steiling K, Timens W, Hiemstra PS, Sterk PJ, Heijink IH, Liu G, Alekseyev YO, Lenburg ME, Spira A, Postma DS. van den Berge M, et al. Among authors: postma ds. Thorax. 2014 Jan;69(1):14-23. doi: 10.1136/thoraxjnl-2012-202878. Epub 2013 Aug 7. Thorax. 2014. PMID: 23925644 Free PMC article. Clinical Trial.
Novel genes for airway wall thickness identified with combined genome-wide association and expression analyses.
Dijkstra AE, Postma DS, van Ginneken B, Wielpütz MO, Schmidt M, Becker N, Owsijewitsch M, Kauczor HU, de Koning HJ, Lammers JW, Oudkerk M, Brandsma CA, Bossé Y, Nickle DC, Sin DD, Hiemstra PS, Wijmenga C, Smolonska J, Zanen P, Vonk JM, van den Berge M, Boezen HM, Groen HJ. Dijkstra AE, et al. Among authors: postma ds. Am J Respir Crit Care Med. 2015 Mar 1;191(5):547-56. doi: 10.1164/rccm.201405-0840OC. Am J Respir Crit Care Med. 2015. PMID: 25517131
Airway hyperresponsiveness in chronic obstructive pulmonary disease: A marker of asthma-chronic obstructive pulmonary disease overlap syndrome?
Tkacova R, Dai DLY, Vonk JM, Leung JM, Hiemstra PS, van den Berge M, Kunz L, Hollander Z, Tashkin D, Wise R, Connett J, Ng R, McManus B, Paul Man SF, Postma DS, Sin DD. Tkacova R, et al. Among authors: postma ds. J Allergy Clin Immunol. 2016 Dec;138(6):1571-1579.e10. doi: 10.1016/j.jaci.2016.04.022. Epub 2016 May 24. J Allergy Clin Immunol. 2016. PMID: 27345171
Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression.
Boudewijn IM, Faiz A, Steiling K, van der Wiel E, Telenga ED, Hoonhorst SJM, Ten Hacken NHT, Brandsma CA, Kerstjens HAM, Timens W, Heijink IH, Jonker MR, de Bruin HG, Sebastiaan Vroegop J, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Spira A, Lenburg ME, Guryev V, Postma DS, van den Berge M. Boudewijn IM, et al. Among authors: postma ds. Respir Res. 2017 Dec 21;18(1):213. doi: 10.1186/s12931-017-0696-5. Respir Res. 2017. PMID: 29268739 Free PMC article. Clinical Trial.
Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids.
Kunz LI, Ten Hacken NH, Lapperre TS, Timens W, Kerstjens HA, van Schadewijk A, Vonk JM, Sont JK, Snoeck-Stroband JB, Postma DS, Sterk PJ, Hiemstra PS; GLUCOLD Study Group. Kunz LI, et al. Among authors: postma ds. Eur Respir J. 2017 Jan 3;49(1):1600839. doi: 10.1183/13993003.00839-2016. Print 2017 Jan. Eur Respir J. 2017. PMID: 28049170 Free article. Clinical Trial.
Clinical and inflammatory determinants of bronchial hyperresponsiveness in COPD.
van den Berge M, Vonk JM, Gosman M, Lapperre TS, Snoeck-Stroband JB, Sterk PJ, Kunz LI, Hiemstra PS, Timens W, Ten Hacken NH, Kerstjens HA, Postma DS. van den Berge M, et al. Among authors: postma ds. Eur Respir J. 2012 Nov;40(5):1098-105. doi: 10.1183/09031936.00169711. Epub 2012 Apr 20. Eur Respir J. 2012. PMID: 22523354 Free article.
897 results