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447 results

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Clinical actionability enhanced through deep targeted sequencing of solid tumors.
Chen K, Meric-Bernstam F, Zhao H, Zhang Q, Ezzeddine N, Tang LY, Qi Y, Mao Y, Chen T, Chong Z, Zhou W, Zheng X, Johnson A, Aldape KD, Routbort MJ, Luthra R, Kopetz S, Davies MA, de Groot J, Moulder S, Vinod R, Farhangfar CJ, Shaw KM, Mendelsohn J, Mills GB, Eterovic AK. Chen K, et al. Among authors: kopetz s. Clin Chem. 2015 Mar;61(3):544-53. doi: 10.1373/clinchem.2014.231100. Epub 2015 Jan 27. Clin Chem. 2015. PMID: 25626406 Free PMC article.
Overcoming resistance to MAPK pathway inhibitors.
Davies MA, Kopetz S. Davies MA, et al. Among authors: kopetz s. J Natl Cancer Inst. 2013 Jan 2;105(1):9-10. doi: 10.1093/jnci/djs507. Epub 2012 Dec 17. J Natl Cancer Inst. 2013. PMID: 23250957 No abstract available.
Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
Mao M, Tian F, Mariadason JM, Tsao CC, Lemos R Jr, Dayyani F, Gopal YN, Jiang ZQ, Wistuba II, Tang XM, Bornman WG, Bollag G, Mills GB, Powis G, Desai J, Gallick GE, Davies MA, Kopetz S. Mao M, et al. Among authors: kopetz s. Clin Cancer Res. 2013 Feb 1;19(3):657-67. doi: 10.1158/1078-0432.CCR-11-1446. Epub 2012 Dec 18. Clin Cancer Res. 2013. PMID: 23251002 Free PMC article.
Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target.
Chen G, Chakravarti N, Aardalen K, Lazar AJ, Tetzlaff MT, Wubbenhorst B, Kim SB, Kopetz S, Ledoux AA, Gopal YN, Pereira CG, Deng W, Lee JS, Nathanson KL, Aldape KD, Prieto VG, Stuart D, Davies MA. Chen G, et al. Among authors: kopetz s. Clin Cancer Res. 2014 Nov 1;20(21):5537-46. doi: 10.1158/1078-0432.CCR-13-3003. Epub 2014 May 6. Clin Cancer Res. 2014. PMID: 24803579 Free PMC article.
Residual tumor thickness at the tumor-normal tissue interface predicts the recurrence-free survival in patients with liver metastasis of breast cancer.
Zhou JH, Rosen D, Andreou A, Brouquet A, Abbott D, Loyer E, Gonzalez-Angulo AM, Kopetz S, Meric-Bernstam F, Kuerer H, Abdalla E, Vauthey JN, Sahin AA, Maru DM. Zhou JH, et al. Among authors: kopetz s. Ann Diagn Pathol. 2014 Oct;18(5):266-70. doi: 10.1016/j.anndiagpath.2014.07.001. Epub 2014 Jul 17. Ann Diagn Pathol. 2014. PMID: 25205085 Free PMC article.
A decision support framework for genomically informed investigational cancer therapy.
Meric-Bernstam F, Johnson A, Holla V, Bailey AM, Brusco L, Chen K, Routbort M, Patel KP, Zeng J, Kopetz S, Davies MA, Piha-Paul SA, Hong DS, Eterovic AK, Tsimberidou AM, Broaddus R, Bernstam EV, Shaw KR, Mendelsohn J, Mills GB. Meric-Bernstam F, et al. Among authors: kopetz s. J Natl Cancer Inst. 2015 Apr 11;107(7):djv098. doi: 10.1093/jnci/djv098. Print 2015 Jul. J Natl Cancer Inst. 2015. PMID: 25863335 Free PMC article. Review.
Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials.
Meric-Bernstam F, Brusco L, Shaw K, Horombe C, Kopetz S, Davies MA, Routbort M, Piha-Paul SA, Janku F, Ueno N, Hong D, De Groot J, Ravi V, Li Y, Luthra R, Patel K, Broaddus R, Mendelsohn J, Mills GB. Meric-Bernstam F, et al. Among authors: kopetz s. J Clin Oncol. 2015 Sep 1;33(25):2753-62. doi: 10.1200/JCO.2014.60.4165. Epub 2015 May 26. J Clin Oncol. 2015. PMID: 26014291 Free PMC article.
Incidental germline variants in 1000 advanced cancers on a prospective somatic genomic profiling protocol.
Meric-Bernstam F, Brusco L, Daniels M, Wathoo C, Bailey AM, Strong L, Shaw K, Lu K, Qi Y, Zhao H, Lara-Guerra H, Litton J, Arun B, Eterovic AK, Aytac U, Routbort M, Subbiah V, Janku F, Davies MA, Kopetz S, Mendelsohn J, Mills GB, Chen K. Meric-Bernstam F, et al. Among authors: kopetz s. Ann Oncol. 2016 May;27(5):795-800. doi: 10.1093/annonc/mdw018. Epub 2016 Jan 19. Ann Oncol. 2016. PMID: 26787237 Free PMC article.
Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials.
Overman MJ, Morris V, Kee B, Fogelman D, Xiao L, Eng C, Dasari A, Shroff R, Mazard T, Shaw K, Vilar E, Raghav K, Shureiqi I, Liang L, Mills GB, Wolff RA, Hamilton S, Meric-Bernstam F, Abbruzzese J, Morris J, Maru D, Kopetz S. Overman MJ, et al. Among authors: kopetz s. Ann Oncol. 2016 Jun;27(6):1068-1074. doi: 10.1093/annonc/mdw073. Epub 2016 Feb 18. Ann Oncol. 2016. PMID: 27045102 Free PMC article. Clinical Trial.
447 results