Liu H - Search Results

1

Discovery and profiling of a selective and efficacious Syk inhibitor.

Thoma G, Smith AB, van Eis MJ, Vangrevelinghe E, Blanz J, Aichholz R, Littlewood-Evans A, Lee CC, Liu H, Zerwes HG. Thoma G, et al. Among authors: liu h. J Med Chem. 2015 Feb 26;58(4):1950-63. doi: 10.1021/jm5018863. Epub 2015 Feb 9. J Med Chem. 2015. PMID: 25633741

2

Discovery of novel purine derivatives with potent and selective inhibitory activity against c-Src tyrosine kinase.

Huang H, Ma J, Shi J, Meng L, Jiang H, Ding J, Liu H. Huang H, et al. Among authors: liu h. Bioorg Med Chem. 2010 Jul 1;18(13):4615-24. doi: 10.1016/j.bmc.2010.05.032. Epub 2010 May 19. Bioorg Med Chem. 2010. PMID: 20570525

3

Current strategies for the discovery of K+ channel modulators.

Ye D, Wang J, Yu K, Zhou Y, Jiang H, Chen K, Liu H. Ye D, et al. Among authors: liu h. Curr Top Med Chem. 2009;9(4):348-61. doi: 10.2174/156802609788317865. Curr Top Med Chem. 2009. PMID: 19442206 Review.

4

One novel quinoxaline derivative as a potent human cyclophilin A inhibitor shows highly inhibitory activity against mouse spleen cell proliferation.

Li J, Chen J, Zhang L, Wang F, Gui C, Zhang L, Qin Y, Xu Q, Liu H, Nan F, Shen J, Bai D, Chen K, Shen X, Jiang H. Li J, et al. Among authors: liu h. Bioorg Med Chem. 2006 Aug 15;14(16):5527-34. doi: 10.1016/j.bmc.2006.04.026. Epub 2006 May 6. Bioorg Med Chem. 2006. PMID: 16682211 Free PMC article.

5

Essential structural profile of a dual functional inhibitor against cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX): molecular docking and 3D-QSAR analyses on DHDMBF analogues.

Zheng M, Zhang Z, Zhu W, Liu H, Luo X, Chen K, Jiang H. Zheng M, et al. Among authors: liu h. Bioorg Med Chem. 2006 May 15;14(10):3428-37. doi: 10.1016/j.bmc.2005.12.062. Epub 2006 Feb 2. Bioorg Med Chem. 2006. PMID: 16458008

6

Tryptophan-containing dipeptide derivatives as potent PPARgamma antagonists: design, synthesis, biological evaluation, and molecular modeling.

Deng G, Liu Z, Ye F, Luo X, Zhu W, Shen X, Liu H, Jiang H. Deng G, et al. Among authors: liu z, liu h. Eur J Med Chem. 2008 Dec;43(12):2699-716. doi: 10.1016/j.ejmech.2008.01.032. Epub 2008 Feb 3. Eur J Med Chem. 2008. PMID: 18329752

7

Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.

Chen L, Li H, Liu J, Zhang L, Liu H, Jiang H. Chen L, et al. Among authors: liu j, liu h. Bioorg Med Chem. 2007 Nov 1;15(21):6763-74. doi: 10.1016/j.bmc.2007.08.003. Epub 2007 Aug 10. Bioorg Med Chem. 2007. PMID: 17719791

8

Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.

He L, Zhang L, Liu X, Li X, Zheng M, Li H, Yu K, Chen K, Shen X, Jiang H, Liu H. He L, et al. Among authors: liu x, liu h. J Med Chem. 2009 Apr 23;52(8):2465-81. doi: 10.1021/jm8015602. J Med Chem. 2009. PMID: 19309082

9

Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.

Liang Z, Zhang L, Li L, Liu J, Li H, Zhang L, Chen L, Cheng K, Zheng M, Wen X, Zhang P, Hao J, Gong Y, Zhang X, Zhu X, Chen J, Liu H, Jiang H, Luo C, Sun H. Liang Z, et al. Among authors: liu j, liu h. Eur J Med Chem. 2011 Jun;46(6):2011-21. doi: 10.1016/j.ejmech.2011.02.053. Epub 2011 Feb 27. Eur J Med Chem. 2011. PMID: 21439694

10

Discovering novel chemical inhibitors of human cyclophilin A: virtual screening, synthesis, and bioassay.

Li J, Chen J, Gui C, Zhang L, Qin Y, Xu Q, Zhang J, Liu H, Shen X, Jiang H. Li J, et al. Among authors: liu h. Bioorg Med Chem. 2006 Apr 1;14(7):2209-24. doi: 10.1016/j.bmc.2005.11.006. Epub 2005 Nov 22. Bioorg Med Chem. 2006. PMID: 16307882 Free PMC article.

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