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Page 1
R-M systems go on the offensive.
Lees J, Gladstone RA. Lees J, et al. Nat Rev Microbiol. 2015 Mar;13(3):131. doi: 10.1038/nrmicro3435. Epub 2015 Feb 2. Nat Rev Microbiol. 2015. PMID: 25639682 No abstract available.
Bacterial GWAS: not just gilding the lily.
Lees JA, Bentley SD. Lees JA, et al. Nat Rev Microbiol. 2016 Jul;14(7):406. doi: 10.1038/nrmicro.2016.82. Epub 2016 May 31. Nat Rev Microbiol. 2016. PMID: 27241043 No abstract available.
Stronger together.
Lees JA, Tonkin-Hill G, Bentley SD. Lees JA, et al. Nat Rev Microbiol. 2017 Sep;15(9):516. doi: 10.1038/nrmicro.2017.95. Epub 2017 Aug 7. Nat Rev Microbiol. 2017. PMID: 28781366 No abstract available.
Fast and flexible bacterial genomic epidemiology with PopPUNK.
Lees JA, Harris SR, Tonkin-Hill G, Gladstone RA, Lo SW, Weiser JN, Corander J, Bentley SD, Croucher NJ. Lees JA, et al. Genome Res. 2019 Feb;29(2):304-316. doi: 10.1101/gr.241455.118. Epub 2019 Jan 24. Genome Res. 2019. PMID: 30679308 Free PMC article.
International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact.
Gladstone RA, Lo SW, Lees JA, Croucher NJ, van Tonder AJ, Corander J, Page AJ, Marttinen P, Bentley LJ, Ochoa TJ, Ho PL, du Plessis M, Cornick JE, Kwambana-Adams B, Benisty R, Nzenze SA, Madhi SA, Hawkins PA, Everett DB, Antonio M, Dagan R, Klugman KP, von Gottberg A, McGee L, Breiman RF, Bentley SD; Global Pneumococcal Sequencing Consortium. Gladstone RA, et al. Among authors: lees ja. EBioMedicine. 2019 May;43:338-346. doi: 10.1016/j.ebiom.2019.04.021. Epub 2019 Apr 16. EBioMedicine. 2019. PMID: 31003929 Free PMC article.
Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis.
Lees JA, Ferwerda B, Kremer PHC, Wheeler NE, Serón MV, Croucher NJ, Gladstone RA, Bootsma HJ, Rots NY, Wijmega-Monsuur AJ, Sanders EAM, Trzciński K, Wyllie AL, Zwinderman AH, van den Berg LH, van Rheenen W, Veldink JH, Harboe ZB, Lundbo LF, de Groot LCPGM, van Schoor NM, van der Velde N, Ängquist LH, Sørensen TIA, Nohr EA, Mentzer AJ, Mills TC, Knight JC, du Plessis M, Nzenze S, Weiser JN, Parkhill J, Madhi S, Benfield T, von Gottberg A, van der Ende A, Brouwer MC, Barrett JC, Bentley SD, van de Beek D. Lees JA, et al. Nat Commun. 2019 May 15;10(1):2176. doi: 10.1038/s41467-019-09976-3. Nat Commun. 2019. PMID: 31092817 Free PMC article.
Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.
Lo SW, Gladstone RA, van Tonder AJ, Lees JA, du Plessis M, Benisty R, Givon-Lavi N, Hawkins PA, Cornick JE, Kwambana-Adams B, Law PY, Ho PL, Antonio M, Everett DB, Dagan R, von Gottberg A, Klugman KP, McGee L, Breiman RF, Bentley SD; Global Pneumococcal Sequencing Consortium. Lo SW, et al. Among authors: lees ja. Lancet Infect Dis. 2019 Jul;19(7):759-769. doi: 10.1016/S1473-3099(19)30297-X. Epub 2019 Jun 10. Lancet Infect Dis. 2019. PMID: 31196809 Free PMC article.
Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates.
Gladstone RA, Lo SW, Goater R, Yeats C, Taylor B, Hadfield J, Lees JA, Croucher NJ, van Tonder AJ, Bentley LJ, Quah FX, Blaschke AJ, Pershing NL, Byington CL, Balaji V, Hryniewicz W, Sigauque B, Ravikumar KL, Almeida SCG, Ochoa TJ, Ho PL, du Plessis M, Ndlangisa KM, Cornick JE, Kwambana-Adams B, Benisty R, Nzenze SA, Madhi SA, Hawkins PA, Pollard AJ, Everett DB, Antonio M, Dagan R, Klugman KP, von Gottberg A, Metcalf BJ, Li Y, Beall BW, McGee L, Breiman RF, Aanensen DM, Bentley SD, The Global Pneumococcal Sequencing Consortium. Gladstone RA, et al. Among authors: lees ja. Microb Genom. 2020 May;6(5):e000357. doi: 10.1099/mgen.0.000357. Epub 2020 Apr 29. Microb Genom. 2020. PMID: 32375991 Free PMC article.
Producing polished prokaryotic pangenomes with the Panaroo pipeline.
Tonkin-Hill G, MacAlasdair N, Ruis C, Weimann A, Horesh G, Lees JA, Gladstone RA, Lo S, Beaudoin C, Floto RA, Frost SDW, Corander J, Bentley SD, Parkhill J. Tonkin-Hill G, et al. Among authors: lees ja. Genome Biol. 2020 Jul 22;21(1):180. doi: 10.1186/s13059-020-02090-4. Genome Biol. 2020. PMID: 32698896 Free PMC article.
1,025 results