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A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis.
Jin P, Andiappan AK, Quek JM, Lee B, Au B, Sio YY, Irwanto A, Schurmann C, Grabe HJ, Suri BK, Matta SA, Westra HJ, Franke L, Esko T, Sun L, Zhang X, Liu H, Zhang F, Larbi A, Xu X, Poidinger M, Liu J, Chew FT, Rotzschke O, Shi L, Wang de Y. Jin P, et al. Among authors: sun l. J Allergy Clin Immunol. 2015 Jun;135(6):1486-93.e8. doi: 10.1016/j.jaci.2014.12.1870. Epub 2015 Jan 30. J Allergy Clin Immunol. 2015. PMID: 25649076
Follow-up analysis of PSORS9 in 151 Chinese families confirmed the linkage to 4q31-32 and refined the evidence to the families of early-onset psoriasis.
Yan KL, Huang W, Zhang XJ, Yang S, Chen YM, Xiao FL, Fan X, Gao M, Cui Y, Zhang GL, Sun LD, Wang PG, Chen JJ, Li W, Chen ZH, Wang ZM, Wang DZ, Zhang KY, Liu JJ. Yan KL, et al. J Invest Dermatol. 2007 Feb;127(2):312-8. doi: 10.1038/sj.jid.5700506. Epub 2006 Nov 30. J Invest Dermatol. 2007. PMID: 17139270 Free article.
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