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Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis.
Dasgupta S, Putluri N, Long W, Zhang B, Wang J, Kaushik AK, Arnold JM, Bhowmik SK, Stashi E, Brennan CA, Rajapakshe K, Coarfa C, Mitsiades N, Ittmann MM, Chinnaiyan AM, Sreekumar A, O'Malley BW. Dasgupta S, et al. Among authors: rajapakshe k. J Clin Invest. 2015 Mar 2;125(3):1174-88. doi: 10.1172/JCI76029. Epub 2015 Feb 9. J Clin Invest. 2015. PMID: 25664849 Free PMC article.
GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex.
He B, Lanz RB, Fiskus W, Geng C, Yi P, Hartig SM, Rajapakshe K, Shou J, Wei L, Shah SS, Foley C, Chew SA, Eedunuri VK, Bedoya DJ, Feng Q, Minami T, Mitsiades CS, Frolov A, Weigel NL, Hilsenbeck SG, Rosen DG, Palzkill T, Ittmann MM, Song Y, Coarfa C, O'Malley BW, Mitsiades N. He B, et al. Among authors: rajapakshe k. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18261-6. doi: 10.1073/pnas.1421415111. Epub 2014 Dec 8. Proc Natl Acad Sci U S A. 2014. PMID: 25489091 Free PMC article.
Comprehensive proteomic profiling identifies the androgen receptor axis and other signaling pathways as targets of microRNAs suppressed in metastatic prostate cancer.
Coarfa C, Fiskus W, Eedunuri VK, Rajapakshe K, Foley C, Chew SA, Shah SS, Geng C, Shou J, Mohamed JS, O'Malley BW, Mitsiades N. Coarfa C, et al. Among authors: rajapakshe k. Oncogene. 2016 May 5;35(18):2345-56. doi: 10.1038/onc.2015.295. Epub 2015 Sep 14. Oncogene. 2016. PMID: 26364608 Free PMC article.
SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis.
Fleet T, Zhang B, Lin F, Zhu B, Dasgupta S, Stashi E, Tackett B, Thevananther S, Rajapakshe KI, Gonzales N, Dean A, Mao J, Timchenko N, Malovannaya A, Qin J, Coarfa C, DeMayo F, Dacso CC, Foulds CE, O'Malley BW, York B. Fleet T, et al. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E6068-77. doi: 10.1073/pnas.1519073112. Epub 2015 Oct 20. Proc Natl Acad Sci U S A. 2015. PMID: 26487680 Free PMC article.
113 results