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Page 1
Principles for computational design of binding antibodies.
Baran D, Pszolla MG, Lapidoth GD, Norn C, Dym O, Unger T, Albeck S, Tyka MD, Fleishman SJ. Baran D, et al. Among authors: norn c. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10900-10905. doi: 10.1073/pnas.1707171114. Epub 2017 Sep 25. Proc Natl Acad Sci U S A. 2017. PMID: 28973872 Free PMC article.
A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen.
Amon R, Grant OC, Leviatan Ben-Arye S, Makeneni S, Nivedha AK, Marshanski T, Norn C, Yu H, Glushka JN, Fleishman SJ, Chen X, Woods RJ, Padler-Karavani V. Amon R, et al. Among authors: norn c. Sci Rep. 2018 Jul 17;8(1):10786. doi: 10.1038/s41598-018-29209-9. Sci Rep. 2018. PMID: 30018351 Free PMC article.
Macromolecular modeling and design in Rosetta: recent methods and frameworks.
Leman JK, Weitzner BD, Lewis SM, Adolf-Bryfogle J, Alam N, Alford RF, Aprahamian M, Baker D, Barlow KA, Barth P, Basanta B, Bender BJ, Blacklock K, Bonet J, Boyken SE, Bradley P, Bystroff C, Conway P, Cooper S, Correia BE, Coventry B, Das R, De Jong RM, DiMaio F, Dsilva L, Dunbrack R, Ford AS, Frenz B, Fu DY, Geniesse C, Goldschmidt L, Gowthaman R, Gray JJ, Gront D, Guffy S, Horowitz S, Huang PS, Huber T, Jacobs TM, Jeliazkov JR, Johnson DK, Kappel K, Karanicolas J, Khakzad H, Khar KR, Khare SD, Khatib F, Khramushin A, King IC, Kleffner R, Koepnick B, Kortemme T, Kuenze G, Kuhlman B, Kuroda D, Labonte JW, Lai JK, Lapidoth G, Leaver-Fay A, Lindert S, Linsky T, London N, Lubin JH, Lyskov S, Maguire J, Malmström L, Marcos E, Marcu O, Marze NA, Meiler J, Moretti R, Mulligan VK, Nerli S, Norn C, Ó'Conchúir S, Ollikainen N, Ovchinnikov S, Pacella MS, Pan X, Park H, Pavlovicz RE, Pethe M, Pierce BG, Pilla KB, Raveh B, Renfrew PD, Burman SSR, Rubenstein A, Sauer MF, Scheck A, Schief W, Schueler-Furman O, Sedan Y, Sevy AM, Sgourakis NG, Shi L, Siegel JB, Silva DA, Smith S, Song Y, Stein A, Szegedy M, Teets FD, Thyme SB, Wang RY, Watkins A, Zimmerman L, Bonneau R. Leman JK, et al. Among authors: norn c. Nat Methods. 2020 Jul;17(7):665-680. doi: 10.1038/s41592-020-0848-2. Epub 2020 Jun 1. Nat Methods. 2020. PMID: 32483333 Free PMC article. Review.
Computational design of protein self-assembly.
Norn CH, André I. Norn CH, et al. Curr Opin Struct Biol. 2016 Aug;39:39-45. doi: 10.1016/j.sbi.2016.04.002. Epub 2016 Apr 26. Curr Opin Struct Biol. 2016. PMID: 27127996 Free article. Review.
De novo protein design by deep network hallucination.
Anishchenko I, Pellock SJ, Chidyausiku TM, Ramelot TA, Ovchinnikov S, Hao J, Bafna K, Norn C, Kang A, Bera AK, DiMaio F, Carter L, Chow CM, Montelione GT, Baker D. Anishchenko I, et al. Among authors: norn c. Nature. 2021 Dec;600(7889):547-552. doi: 10.1038/s41586-021-04184-w. Epub 2021 Dec 1. Nature. 2021. PMID: 34853475 Free PMC article.
Protein sequence design by conformational landscape optimization.
Norn C, Wicky BIM, Juergens D, Liu S, Kim D, Tischer D, Koepnick B, Anishchenko I; Foldit Players; Baker D, Ovchinnikov S. Norn C, et al. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2017228118. doi: 10.1073/pnas.2017228118. Proc Natl Acad Sci U S A. 2021. PMID: 33712545 Free PMC article.
21 results