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The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma.
Barneda-Zahonero B, Collazo O, Azagra A, Fernández-Duran I, Serra-Musach J, Islam AB, Vega-García N, Malatesta R, Camós M, Gómez A, Román-González L, Vidal A, López-Bigas N, Villanueva A, Esteller M, Parra M. Barneda-Zahonero B, et al. Cell Death Dis. 2015 Feb 12;6(2):e1635. doi: 10.1038/cddis.2014.594. Cell Death Dis. 2015. PMID: 25675295 Free PMC article.
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer.
Rodilla V, Villanueva A, Obrador-Hevia A, Robert-Moreno A, Fernández-Majada V, Grilli A, López-Bigas N, Bellora N, Albà MM, Torres F, Duñach M, Sanjuan X, Gonzalez S, Gridley T, Capella G, Bigas A, Espinosa L. Rodilla V, et al. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6315-20. doi: 10.1073/pnas.0813221106. Epub 2009 Mar 26. Proc Natl Acad Sci U S A. 2009. PMID: 19325125 Free PMC article.
Whole genome analysis of p38 SAPK-mediated gene expression upon stress.
Ferreiro I, Joaquin M, Islam A, Gomez-Lopez G, Barragan M, Lombardía L, Domínguez O, Pisano DG, Lopez-Bigas N, Nebreda AR, Posas F. Ferreiro I, et al. BMC Genomics. 2010 Mar 1;11:144. doi: 10.1186/1471-2164-11-144. BMC Genomics. 2010. PMID: 20187982 Free PMC article.
Selective targeting of histone methylation.
Islam AB, Richter WF, Lopez-Bigas N, Benevolenskaya EV. Islam AB, et al. Cell Cycle. 2011 Feb 1;10(3):413-24. doi: 10.4161/cc.10.3.14705. Epub 2011 Feb 1. Cell Cycle. 2011. PMID: 21270517 Free PMC article.
Co-regulation of histone-modifying enzymes in cancer.
Islam AB, Richter WF, Jacobs LA, Lopez-Bigas N, Benevolenskaya EV. Islam AB, et al. PLoS One. 2011;6(8):e24023. doi: 10.1371/journal.pone.0024023. Epub 2011 Aug 23. PLoS One. 2011. PMID: 21886846 Free PMC article.
166 results