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The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma.
Cell Death Dis. 2015 Feb 12;6(2):e1635. doi: 10.1038/cddis.2014.594.
Cell Death Dis. 2015.
PMID: 25675295
Free PMC article.
HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages.
Barneda-Zahonero B, Román-González L, Collazo O, Rafati H, Islam AB, Bussmann LH, di Tullio A, De Andres L, Graf T, López-Bigas N, Mahmoudi T, Parra M.
Barneda-Zahonero B, et al. Among authors: roman gonzalez l.
PLoS Genet. 2013 May;9(5):e1003503. doi: 10.1371/journal.pgen.1003503. Epub 2013 May 16.
PLoS Genet. 2013.
PMID: 23696748
Free PMC article.
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In vivo conditional deletion of HDAC7 reveals its requirement to establish proper B lymphocyte identity and development.
Azagra A, Román-González L, Collazo O, Rodríguez-Ubreva J, de Yébenes VG, Barneda-Zahonero B, Rodríguez J, Castro de Moura M, Grego-Bessa J, Fernández-Duran I, Islam AB, Esteller M, Ramiro AR, Ballestar E, Parra M.
Azagra A, et al. Among authors: roman gonzalez l.
J Exp Med. 2016 Nov 14;213(12):2591-2601. doi: 10.1084/jem.20150821. Epub 2016 Oct 17.
J Exp Med. 2016.
PMID: 27810920
Free PMC article.
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Epigenetic regulation of B lymphocyte differentiation, transdifferentiation, and reprogramming.
Barneda-Zahonero B, Roman-Gonzalez L, Collazo O, Mahmoudi T, Parra M.
Barneda-Zahonero B, et al. Among authors: roman gonzalez l.
Comp Funct Genomics. 2012;2012:564381. doi: 10.1155/2012/564381. Epub 2012 Aug 26.
Comp Funct Genomics. 2012.
PMID: 22997486
Free PMC article.
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Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells.
Tian YF, Ahn H, Schneider RS, Yang SN, Roman-Gonzalez L, Melnick AM, Cerchietti L, Singh A.
Tian YF, et al. Among authors: roman gonzalez l.
Biomaterials. 2015 Dec;73:110-9. doi: 10.1016/j.biomaterials.2015.09.007. Epub 2015 Sep 11.
Biomaterials. 2015.
PMID: 26406451
Free PMC article.
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