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GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb.
den Hoed M, Strawbridge RJ, Almgren P, Gustafsson S, Axelsson T, Engström G, de Faire U, Hedblad B, Humphries SE, Lindgren CM, Morris AP, Östling G, Syvänen AC, Tremoli E, Hamsten A, Ingelsson E, Melander O, Lind L. den Hoed M, et al. Among authors: humphries se. Atherosclerosis. 2015 Apr;239(2):304-10. doi: 10.1016/j.atherosclerosis.2015.01.032. Epub 2015 Jan 31. Atherosclerosis. 2015. PMID: 25682028 Free PMC article.
Factor VII Arg/Gln353 polymorphism determines factor VII coagulant activity in patients with myocardial infarction (MI) and control subjects in Belfast and in France but is not a strong indicator of MI risk in the ECTIM study.
Lane A, Green F, Scarabin PY, Nicaud V, Bara L, Humphries S, Evans A, Luc G, Cambou JP, Arveiler D, Cambien F. Lane A, et al. Atherosclerosis. 1996 Jan 5;119(1):119-27. doi: 10.1016/0021-9150(95)05638-6. Atherosclerosis. 1996. PMID: 8929253
843 results