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Characterization of two isoforms of the skeletal muscle LIM protein 1, SLIM1. Localization of SLIM1 at focal adhesions and the isoform slimmer in the nucleus of myoblasts and cytoplasm of myotubes suggests distinct roles in the cytoskeleton and in nuclear-cytoplasmic communication.
Brown S, McGrath MJ, Ooms LM, Gurung R, Maimone MM, Mitchell CA. Brown S, et al. Among authors: mcgrath mj. J Biol Chem. 1999 Sep 17;274(38):27083-91. doi: 10.1074/jbc.274.38.27083. J Biol Chem. 1999. PMID: 10480922 Free article.
Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles following epidermal growth factor stimulation.
Gurung R, Tan A, Ooms LM, McGrath MJ, Huysmans RD, Munday AD, Prescott M, Whisstock JC, Mitchell CA. Gurung R, et al. Among authors: mcgrath mj. J Biol Chem. 2003 Mar 28;278(13):11376-85. doi: 10.1074/jbc.M209991200. Epub 2003 Jan 20. J Biol Chem. 2003. PMID: 12536145 Free article.
FHL3 is an actin-binding protein that regulates alpha-actinin-mediated actin bundling: FHL3 localizes to actin stress fibers and enhances cell spreading and stress fiber disassembly.
Coghill ID, Brown S, Cottle DL, McGrath MJ, Robinson PA, Nandurkar HH, Dyson JM, Mitchell CA. Coghill ID, et al. Among authors: mcgrath mj. J Biol Chem. 2003 Jun 27;278(26):24139-52. doi: 10.1074/jbc.M213259200. Epub 2003 Apr 18. J Biol Chem. 2003. PMID: 12704194 Free article.
FHL3 binds MyoD and negatively regulates myotube formation.
Cottle DL, McGrath MJ, Cowling BS, Coghill ID, Brown S, Mitchell CA. Cottle DL, et al. Among authors: mcgrath mj. J Cell Sci. 2007 Apr 15;120(Pt 8):1423-35. doi: 10.1242/jcs.004739. Epub 2007 Mar 27. J Cell Sci. 2007. PMID: 17389685
Proteomic identification of FHL1 as the protein mutated in human reducing body myopathy.
Schessl J, Zou Y, McGrath MJ, Cowling BS, Maiti B, Chin SS, Sewry C, Battini R, Hu Y, Cottle DL, Rosenblatt M, Spruce L, Ganguly A, Kirschner J, Judkins AR, Golden JA, Goebel HH, Muntoni F, Flanigan KM, Mitchell CA, Bönnemann CG. Schessl J, et al. Among authors: mcgrath mj. J Clin Invest. 2008 Mar;118(3):904-12. doi: 10.1172/JCI34450. J Clin Invest. 2008. PMID: 18274675 Free PMC article.
127 results