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Microsatellite instable and microsatellite stable primary endometrial carcinoma cells and their subcutaneous and orthotopic xenografts recapitulate the characteristics of the corresponding primary tumor.
Schrauwen S, Coenegrachts L, Depreeuw J, Luyten C, Verbist G, Debruyne D, Vergote I, Lambrechts D, Amant F. Schrauwen S, et al. Among authors: depreeuw j. Int J Gynecol Cancer. 2015 Mar;25(3):363-71. doi: 10.1097/IGC.0000000000000363. Int J Gynecol Cancer. 2015. PMID: 25695543
Dual blockade of PI3K/AKT/mTOR (NVP-BEZ235) and Ras/Raf/MEK (AZD6244) pathways synergistically inhibit growth of primary endometrioid endometrial carcinoma cultures, whereas NVP-BEZ235 reduces tumor growth in the corresponding xenograft models.
Schrauwen S, Depreeuw J, Coenegrachts L, Hermans E, Lambrechts D, Amant F. Schrauwen S, et al. Among authors: depreeuw j. Gynecol Oncol. 2015 Jul;138(1):165-73. doi: 10.1016/j.ygyno.2015.04.028. Epub 2015 Apr 28. Gynecol Oncol. 2015. PMID: 25933683 Free article.
Mutation profile and clinical outcome of mixed endometrioid-serous endometrial carcinomas are different from that of pure endometrioid or serous carcinomas.
Coenegrachts L, Garcia-Dios DA, Depreeuw J, Santacana M, Gatius S, Zikan M, Moerman P, Verbist L, Lambrechts D, Matias-Guiu X, Amant F. Coenegrachts L, et al. Among authors: depreeuw j. Virchows Arch. 2015 Apr;466(4):415-22. doi: 10.1007/s00428-015-1728-5. Epub 2015 Feb 13. Virchows Arch. 2015. PMID: 25677978 Free article.
Successful application of endoscopic ultrasound-guided fine needle biopsy to establish pancreatic patient-derived tumor xenografts: a pilot study.
Hermans E, Van der Merwe SW, Depreeuw J, Dekervel J, Radaelli E, Roskams T, van Pelt Jos J, Topal B, Verslype C, Prenen H, Van Steenbergen W, Nevens F, Lambrechts D, Amant F. Hermans E, et al. Among authors: depreeuw j. Endoscopy. 2016 Nov;48(11):1016-1022. doi: 10.1055/s-0042-113597. Epub 2016 Sep 14. Endoscopy. 2016. PMID: 27626319
Amplification of 1q32.1 Refines the Molecular Classification of Endometrial Carcinoma.
Depreeuw J, Stelloo E, Osse EM, Creutzberg CL, Nout RA, Moisse M, Garcia-Dios DA, Dewaele M, Willekens K, Marine JC, Matias-Guiu X, Amant F, Lambrechts D, Bosse T. Depreeuw J, et al. Clin Cancer Res. 2017 Dec 1;23(23):7232-7241. doi: 10.1158/1078-0432.CCR-17-0566. Epub 2017 Sep 22. Clin Cancer Res. 2017. PMID: 28939739
Prognostic significance of POLE proofreading mutations in endometrial cancer.
Church DN, Stelloo E, Nout RA, Valtcheva N, Depreeuw J, ter Haar N, Noske A, Amant F, Tomlinson IP, Wild PJ, Lambrechts D, Jürgenliemk-Schulz IM, Jobsen JJ, Smit VT, Creutzberg CL, Bosse T. Church DN, et al. Among authors: depreeuw j. J Natl Cancer Inst. 2014 Dec 12;107(1):402. doi: 10.1093/jnci/dju402. Print 2015 Jan. J Natl Cancer Inst. 2014. PMID: 25505230 Free PMC article.
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