El Oualid F - Search Results

1

Mechanism of UCH-L5 activation and inhibition by DEUBAD domains in RPN13 and INO80G.

Sahtoe DD, van Dijk WJ, El Oualid F, Ekkebus R, Ovaa H, Sixma TK. Sahtoe DD, et al. Among authors: el oualid f. Mol Cell. 2015 Mar 5;57(5):887-900. doi: 10.1016/j.molcel.2014.12.039. Epub 2015 Feb 19. Mol Cell. 2015. PMID: 25702870 Free PMC article.

2

Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.

Kim RQ, Geurink PP, Mulder MPC, Fish A, Ekkebus R, El Oualid F, van Dijk WJ, van Dalen D, Ovaa H, van Ingen H, Sixma TK. Kim RQ, et al. Among authors: el oualid f. Nat Commun. 2019 Jan 16;10(1):231. doi: 10.1038/s41467-018-08231-5. Nat Commun. 2019. PMID: 30651545 Free PMC article.

3

Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes.

Shanmugham A, Fish A, Luna-Vargas MP, Faesen AC, El Oualid F, Sixma TK, Ovaa H. Shanmugham A, et al. Among authors: el oualid f. J Am Chem Soc. 2010 Jul 7;132(26):8834-5. doi: 10.1021/ja101803s. J Am Chem Soc. 2010. PMID: 20540574

4

Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin.

El Oualid F, Merkx R, Ekkebus R, Hameed DS, Smit JJ, de Jong A, Hilkmann H, Sixma TK, Ovaa H. El Oualid F, et al. Angew Chem Int Ed Engl. 2010 Dec 27;49(52):10149-53. doi: 10.1002/anie.201005995. Angew Chem Int Ed Engl. 2010. PMID: 21117055 Free PMC article. No abstract available.

5

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

Faesen AC, Luna-Vargas MP, Geurink PP, Clerici M, Merkx R, van Dijk WJ, Hameed DS, El Oualid F, Ovaa H, Sixma TK. Faesen AC, et al. Among authors: el oualid f. Chem Biol. 2011 Dec 23;18(12):1550-61. doi: 10.1016/j.chembiol.2011.10.017. Chem Biol. 2011. PMID: 22195557

6

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

Mevissen TE, Hospenthal MK, Geurink PP, Elliott PR, Akutsu M, Arnaudo N, Ekkebus R, Kulathu Y, Wauer T, El Oualid F, Freund SM, Ovaa H, Komander D. Mevissen TE, et al. Among authors: el oualid f. Cell. 2013 Jul 3;154(1):169-84. doi: 10.1016/j.cell.2013.05.046. Cell. 2013. PMID: 23827681 Free PMC article.

7

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains.

Licchesi JD, Mieszczanek J, Mevissen TE, Rutherford TJ, Akutsu M, Virdee S, El Oualid F, Chin JW, Ovaa H, Bienz M, Komander D. Licchesi JD, et al. Among authors: el oualid f. Nat Struct Mol Biol. 2011 Dec 11;19(1):62-71. doi: 10.1038/nsmb.2169. Nat Struct Mol Biol. 2011. PMID: 22157957 Free PMC article.

8

A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents.

Geurink PP, El Oualid F, Jonker A, Hameed DS, Ovaa H. Geurink PP, et al. Among authors: el oualid f. Chembiochem. 2012 Jan 23;13(2):293-7. doi: 10.1002/cbic.201100706. Epub 2011 Dec 23. Chembiochem. 2012. PMID: 22213387 Free PMC article. No abstract available.

9

A native chemical ligation handle that enables the synthesis of advanced activity-based probes: diubiquitin as a case study.

Mulder MP, El Oualid F, ter Beek J, Ovaa H. Mulder MP, et al. Among authors: el oualid f. Chembiochem. 2014 May 5;15(7):946-9. doi: 10.1002/cbic.201402012. Epub 2014 Mar 12. Chembiochem. 2014. PMID: 24623714 Free PMC article.

10

Polyubiquitin-Photoactivatable Crosslinking Reagents for Mapping Ubiquitin Interactome Identify Rpn1 as a Proteasome Ubiquitin-Associating Subunit.

Chojnacki M, Mansour W, Hameed DS, Singh RK, El Oualid F, Rosenzweig R, Nakasone MA, Yu Z, Glaser F, Kay LE, Fushman D, Ovaa H, Glickman MH. Chojnacki M, et al. Among authors: el oualid f. Cell Chem Biol. 2017 Apr 20;24(4):443-457.e6. doi: 10.1016/j.chembiol.2017.02.013. Epub 2017 Mar 16. Cell Chem Biol. 2017. PMID: 28330605 Free PMC article.

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