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Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling.
Sumida T, Naito AT, Nomura S, Nakagawa A, Higo T, Hashimoto A, Okada K, Sakai T, Ito M, Yamaguchi T, Oka T, Akazawa H, Lee JK, Minamino T, Offermanns S, Noda T, Botto M, Kobayashi Y, Morita H, Manabe I, Nagai T, Shiojima I, Komuro I. Sumida T, et al. Among authors: manabe i. Nat Commun. 2015 Feb 26;6:6241. doi: 10.1038/ncomms7241. Nat Commun. 2015. PMID: 25716000 Free PMC article.
Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.
Shindo T, Manabe I, Fukushima Y, Tobe K, Aizawa K, Miyamoto S, Kawai-Kowase K, Moriyama N, Imai Y, Kawakami H, Nishimatsu H, Ishikawa T, Suzuki T, Morita H, Maemura K, Sata M, Hirata Y, Komukai M, Kagechika H, Kadowaki T, Kurabayashi M, Nagai R. Shindo T, et al. Among authors: manabe i. Nat Med. 2002 Aug;8(8):856-63. doi: 10.1038/nm738. Epub 2002 Jul 8. Nat Med. 2002. PMID: 12101409
Vasorin, a transforming growth factor beta-binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo.
Ikeda Y, Imai Y, Kumagai H, Nosaka T, Morikawa Y, Hisaoka T, Manabe I, Maemura K, Nakaoka T, Imamura T, Miyazono K, Komuro I, Nagai R, Kitamura T. Ikeda Y, et al. Among authors: manabe i. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10732-7. doi: 10.1073/pnas.0404117101. Epub 2004 Jul 9. Proc Natl Acad Sci U S A. 2004. PMID: 15247411 Free PMC article.
Angiotensin II impairs endothelial nitric-oxide synthase bioavailability under free cholesterol-enriched conditions via intracellular free cholesterol-rich membrane microdomains.
Amiya E, Watanabe M, Takeda N, Saito T, Shiga T, Hosoya Y, Nakao T, Imai Y, Manabe I, Nagai R, Komuro I, Maemura K. Amiya E, et al. Among authors: manabe i. J Biol Chem. 2013 May 17;288(20):14497-14509. doi: 10.1074/jbc.M112.448522. Epub 2013 Apr 2. J Biol Chem. 2013. PMID: 23548909 Free PMC article.
Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis.
Tanaka M, Ikeda K, Suganami T, Komiya C, Ochi K, Shirakawa I, Hamaguchi M, Nishimura S, Manabe I, Matsuda T, Kimura K, Inoue H, Inagaki Y, Aoe S, Yamasaki S, Ogawa Y. Tanaka M, et al. Among authors: manabe i. Nat Commun. 2014 Sep 19;5:4982. doi: 10.1038/ncomms5982. Nat Commun. 2014. PMID: 25236782 Free article.
184 results