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Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling.
Sumida T, Naito AT, Nomura S, Nakagawa A, Higo T, Hashimoto A, Okada K, Sakai T, Ito M, Yamaguchi T, Oka T, Akazawa H, Lee JK, Minamino T, Offermanns S, Noda T, Botto M, Kobayashi Y, Morita H, Manabe I, Nagai T, Shiojima I, Komuro I. Sumida T, et al. Among authors: naito at. Nat Commun. 2015 Feb 26;6:6241. doi: 10.1038/ncomms7241. Nat Commun. 2015. PMID: 25716000 Free PMC article.
IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis.
Zhu W, Shiojima I, Ito Y, Li Z, Ikeda H, Yoshida M, Naito AT, Nishi J, Ueno H, Umezawa A, Minamino T, Nagai T, Kikuchi A, Asashima M, Komuro I. Zhu W, et al. Among authors: naito at. Nature. 2008 Jul 17;454(7202):345-9. doi: 10.1038/nature07027. Epub 2008 Jun 4. Nature. 2008. PMID: 18528331
Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes.
Naito AT, Sumida T, Nomura S, Liu ML, Higo T, Nakagawa A, Okada K, Sakai T, Hashimoto A, Hara Y, Shimizu I, Zhu W, Toko H, Katada A, Akazawa H, Oka T, Lee JK, Minamino T, Nagai T, Walsh K, Kikuchi A, Matsumoto M, Botto M, Shiojima I, Komuro I. Naito AT, et al. Cell. 2012 Jun 8;149(6):1298-313. doi: 10.1016/j.cell.2012.03.047. Cell. 2012. PMID: 22682250 Free PMC article.
Wnt/β-Catenin Signaling Contributes to Skeletal Myopathy in Heart Failure via Direct Interaction With Forkhead Box O.
Okada K, Naito AT, Higo T, Nakagawa A, Shibamoto M, Sakai T, Hashimoto A, Kuramoto Y, Sumida T, Nomura S, Ito M, Yamaguchi T, Oka T, Akazawa H, Lee JK, Morimoto S, Sakata Y, Shiojima I, Komuro I. Okada K, et al. Among authors: naito at. Circ Heart Fail. 2015 Jul;8(4):799-808. doi: 10.1161/CIRCHEARTFAILURE.114.001958. Epub 2015 Jun 2. Circ Heart Fail. 2015. PMID: 26038536
Activation of endothelial β-catenin signaling induces heart failure.
Nakagawa A, Naito AT, Sumida T, Nomura S, Shibamoto M, Higo T, Okada K, Sakai T, Hashimoto A, Kuramoto Y, Oka T, Lee JK, Harada M, Ueda K, Shiojima I, Limbourg FP, Adams RH, Noda T, Sakata Y, Akazawa H, Komuro I. Nakagawa A, et al. Among authors: naito at. Sci Rep. 2016 May 5;6:25009. doi: 10.1038/srep25009. Sci Rep. 2016. PMID: 27146149 Free PMC article.
DNA single-strand break-induced DNA damage response causes heart failure.
Higo T, Naito AT, Sumida T, Shibamoto M, Okada K, Nomura S, Nakagawa A, Yamaguchi T, Sakai T, Hashimoto A, Kuramoto Y, Ito M, Hikoso S, Akazawa H, Lee JK, Shiojima I, McKinnon PJ, Sakata Y, Komuro I. Higo T, et al. Among authors: naito at. Nat Commun. 2017 Apr 24;8:15104. doi: 10.1038/ncomms15104. Nat Commun. 2017. PMID: 28436431 Free PMC article.
Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure.
Nomura S, Satoh M, Fujita T, Higo T, Sumida T, Ko T, Yamaguchi T, Tobita T, Naito AT, Ito M, Fujita K, Harada M, Toko H, Kobayashi Y, Ito K, Takimoto E, Akazawa H, Morita H, Aburatani H, Komuro I. Nomura S, et al. Among authors: naito at. Nat Commun. 2018 Oct 30;9(1):4435. doi: 10.1038/s41467-018-06639-7. Nat Commun. 2018. PMID: 30375404 Free PMC article.
80 results