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Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors.
McKittrick BA, Caldwell JP, Bara T, Boykow G, Chintala M, Clader J, Czarniecki M, Courneya B, Duffy R, Fleming L, Giessert R, Greenlee WJ, Heap C, Hong L, Huang Y, Iserloh U, Josien H, Khan T, Korfmacher W, Liang X, Mazzola R, Mitra S, Moore K, Orth P, Rajagopalan M, Roy S, Sakwa S, Strickland C, Vaccaro H, Voigt J, Wang H, Wong J, Zhang R, Zych A. McKittrick BA, et al. Among authors: giessert r. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1592-6. doi: 10.1016/j.bmcl.2015.02.003. Epub 2015 Feb 10. Bioorg Med Chem Lett. 2015. PMID: 25728416
Self-complementary purines by quadruple hydrogen bonding.
Martin AM, Butler RS, Ghiviriga I, Giessert RE, Abboud KA, Castellano RK. Martin AM, et al. Among authors: giessert re. Chem Commun (Camb). 2006 Nov 13;(42):4413-5. doi: 10.1039/b610239e. Epub 2006 Sep 7. Chem Commun (Camb). 2006. PMID: 17057861