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The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages.
Luhmann UF, Robbie S, Munro PM, Barker SE, Duran Y, Luong V, Fitzke FW, Bainbridge JW, Ali RR, MacLaren RE. Luhmann UF, et al. Among authors: maclaren re. Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5934-43. doi: 10.1167/iovs.09-3462. Epub 2009 Jul 2. Invest Ophthalmol Vis Sci. 2009. PMID: 19578022 Free PMC article.
Characterization of a dominant cone degeneration in a green fluorescent protein-reporter mouse with disruption of Loci associated with human dominant retinal dystrophy.
Lipinski DM, Yusuf M, Barnard AR, Damant C, Charbel Issa P, Singh MS, Lee E, Davies WL, Volpi EV, MacLaren RE. Lipinski DM, et al. Among authors: maclaren re. Invest Ophthalmol Vis Sci. 2011 Aug 22;52(9):6617-23. doi: 10.1167/iovs.11-7932. Invest Ophthalmol Vis Sci. 2011. PMID: 21705682 Free PMC article.
Recessive mutations in TSPAN12 cause retinal dysplasia and severe familial exudative vitreoretinopathy (FEVR).
Poulter JA, Davidson AE, Ali M, Gilmour DF, Parry DA, Mintz-Hittner HA, Carr IM, Bottomley HM, Long VW, Downey LM, Sergouniotis PI, Wright GA, MacLaren RE, Moore AT, Webster AR, Inglehearn CF, Toomes C. Poulter JA, et al. Among authors: maclaren re. Invest Ophthalmol Vis Sci. 2012 May 14;53(6):2873-9. doi: 10.1167/iovs.11-8629. Invest Ophthalmol Vis Sci. 2012. PMID: 22427576
358 results