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The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging.
Gottschalk WK, Lutz MW, He YT, Saunders AM, Burns DK, Roses AD, Chiba-Falek O. Gottschalk WK, et al. Among authors: saunders am. J Parkinsons Dis Alzheimers Dis. 2014 Nov;1(1):12. doi: 10.13188/2376-922X.1000003. J Parkinsons Dis Alzheimers Dis. 2014. PMID: 25745640 Free PMC article.
Genetic variation at a single locus and age of onset for Alzheimer's disease.
Lutz MW, Crenshaw DG, Saunders AM, Roses AD. Lutz MW, et al. Among authors: saunders am. Alzheimers Dement. 2010 Mar;6(2):125-31. doi: 10.1016/j.jalz.2010.01.011. Alzheimers Dement. 2010. PMID: 20298972 Free PMC article.
The significant finding discussed here is that a variable-length, deoxythymidine homopolymer (poly-T) within intron 6 of the TOMM40 gene is associated with the age of onset of LOAD [Roses AD, Lutz MW, Amrine-Madsen H, Saunders AM, Crenshaw DG, Sundseth SS, et al. A …
The significant finding discussed here is that a variable-length, deoxythymidine homopolymer (poly-T) within intron 6 of the TOMM40 gene is …
The importance of being connected.
Lutz MW, Crenshaw DG, Saunders AM, Roses AD. Lutz MW, et al. Among authors: saunders am. J Alzheimers Dis. 2011;24(2):247-51. doi: 10.3233/JAD-2010-101765. J Alzheimers Dis. 2011. PMID: 21206004 No abstract available.
New applications of disease genetics and pharmacogenetics to drug development.
Roses AD, Saunders AM, Lutz MW, Zhang N, Hariri AR, Asin KE, Crenshaw DG, Budur K, Burns DK, Brannan SK. Roses AD, et al. Among authors: saunders am. Curr Opin Pharmacol. 2014 Feb;14:81-9. doi: 10.1016/j.coph.2013.12.002. Epub 2014 Jan 3. Curr Opin Pharmacol. 2014. PMID: 24565016 Free article. Review.
African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles.
Roses AD, Lutz MW, Saunders AM, Goldgaber D, Saul R, Sundseth SS, Akkari PA, Roses SM, Gottschalk WK, Whitfield KE, Vostrov AA, Hauser MA, Allingham RR, Burns DK, Chiba-Falek O, Welsh-Bohmer KA. Roses AD, et al. Among authors: saunders am. Alzheimers Dement. 2014 Nov;10(6):592-601.e2. doi: 10.1016/j.jalz.2014.06.009. Epub 2014 Sep 26. Alzheimers Dement. 2014. PMID: 25260913 Free article.
The Alu neurodegeneration hypothesis: A primate-specific mechanism for neuronal transcription noise, mitochondrial dysfunction, and manifestation of neurodegenerative disease.
Larsen PA, Lutz MW, Hunnicutt KE, Mihovilovic M, Saunders AM, Yoder AD, Roses AD. Larsen PA, et al. Among authors: saunders am. Alzheimers Dement. 2017 Jul;13(7):828-838. doi: 10.1016/j.jalz.2017.01.017. Epub 2017 Feb 24. Alzheimers Dement. 2017. PMID: 28242298 Free PMC article.
279 results