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Human monocytes undergo functional re-programming during sepsis mediated by hypoxia-inducible factor-1α.
Shalova IN, Lim JY, Chittezhath M, Zinkernagel AS, Beasley F, Hernández-Jiménez E, Toledano V, Cubillos-Zapata C, Rapisarda A, Chen J, Duan K, Yang H, Poidinger M, Melillo G, Nizet V, Arnalich F, López-Collazo E, Biswas SK. Shalova IN, et al. Immunity. 2015 Mar 17;42(3):484-98. doi: 10.1016/j.immuni.2015.02.001. Epub 2015 Mar 3. Immunity. 2015. PMID: 25746953 Free article.
Mitochondrial DAMPs induce endotoxin tolerance in human monocytes: an observation in patients with myocardial infarction.
Fernández-Ruiz I, Arnalich F, Cubillos-Zapata C, Hernández-Jiménez E, Moreno-González R, Toledano V, Fernández-Velasco M, Vallejo-Cremades MT, Esteban-Burgos L, de Diego RP, Llamas-Matias MA, García-Arumi E, Martí R, Boscá L, Andreu AL, López-Sendón JL, López-Collazo E. Fernández-Ruiz I, et al. PLoS One. 2014 May 5;9(5):e95073. doi: 10.1371/journal.pone.0095073. eCollection 2014. PLoS One. 2014. PMID: 24797663 Free PMC article. Clinical Trial.
NFκB2/p100 is a key factor for endotoxin tolerance in human monocytes: a demonstration using primary human monocytes from patients with sepsis.
Cubillos-Zapata C, Hernández-Jiménez E, Toledano V, Esteban-Burgos L, Fernández-Ruíz I, Gómez-Piña V, Del Fresno C, Siliceo M, Prieto-Chinchiña P, Pérez de Diego R, Boscá L, Fresno M, Arnalich F, López-Collazo E. Cubillos-Zapata C, et al. J Immunol. 2014 Oct 15;193(8):4195-202. doi: 10.4049/jimmunol.1400721. Epub 2014 Sep 15. J Immunol. 2014. PMID: 25225662
Circulating Monocytes Exhibit an Endotoxin Tolerance Status after Acute Ischemic Stroke: Mitochondrial DNA as a Putative Explanation for Poststroke Infections.
Hernández-Jiménez E, Gutierrez-Fernández M, Cubillos-Zapata C, Otero-Ortega L, Rodríguez-Frutos B, Toledano V, Martínez-Sánchez P, Fuentes B, Varela-Serrano A, Avendaño-Ortiz J, Blázquez A, Mangas-Guijarro MÁ, Díez-Tejedor E, López-Collazo E. Hernández-Jiménez E, et al. J Immunol. 2017 Mar 1;198(5):2038-2046. doi: 10.4049/jimmunol.1601594. Epub 2017 Jan 23. J Immunol. 2017. PMID: 28115526
PD-L1 Overexpression During Endotoxin Tolerance Impairs the Adaptive Immune Response in Septic Patients via HIF1α.
Avendaño-Ortiz J, Maroun-Eid C, Martín-Quirós A, Toledano V, Cubillos-Zapata C, Gómez-Campelo P, Varela-Serrano A, Casas-Martin J, Llanos-González E, Alvarez E, García-Río F, Aguirre LA, Hernández-Jiménez E, López-Collazo E. Avendaño-Ortiz J, et al. Among authors: hernandez jimenez e. J Infect Dis. 2018 Jan 17;217(3):393-404. doi: 10.1093/infdis/jix279. J Infect Dis. 2018. PMID: 28973671
Obstructive Sleep Apnea Monocytes Exhibit High Levels of Vascular Endothelial Growth Factor Secretion, Augmenting Tumor Progression.
Cubillos-Zapata C, Hernández-Jiménez E, Avendaño-Ortiz J, Toledano V, Varela-Serrano A, Fernández-Navarro I, Casitas R, Carpio C, Aguirre LA, García-Río F, López-Collazo E. Cubillos-Zapata C, et al. Among authors: hernandez jimenez e. Mediators Inflamm. 2018 May 28;2018:7373921. doi: 10.1155/2018/7373921. eCollection 2018. Mediators Inflamm. 2018. PMID: 29997451 Free PMC article.
Biofilm vs. planktonic bacterial mode of growth: which do human macrophages prefer?
Hernández-Jiménez E, Del Campo R, Toledano V, Vallejo-Cremades MT, Muñoz A, Largo C, Arnalich F, García-Rio F, Cubillos-Zapata C, López-Collazo E. Hernández-Jiménez E, et al. Biochem Biophys Res Commun. 2013 Nov 29;441(4):947-52. doi: 10.1016/j.bbrc.2013.11.012. Epub 2013 Nov 14. Biochem Biophys Res Commun. 2013. PMID: 24239884
Chronic lymphocytic leukemia: a paradigm of innate immune cross-tolerance.
Jurado-Camino T, Córdoba R, Esteban-Burgos L, Hernández-Jiménez E, Toledano V, Hernandez-Rivas JA, Ruiz-Sainz E, Cobo T, Siliceo M, Perez de Diego R, Belda C, Cubillos-Zapata C, López-Collazo E. Jurado-Camino T, et al. J Immunol. 2015 Jan 15;194(2):719-27. doi: 10.4049/jimmunol.1402272. Epub 2014 Dec 10. J Immunol. 2015. PMID: 25505275 Clinical Trial.
A System Dynamics Model to Predict the Human Monocyte Response to Endotoxins.
Álvarez E, Toledano V, Morilla F, Hernández-Jiménez E, Cubillos-Zapata C, Varela-Serrano A, Casas-Martín J, Avendaño-Ortiz J, Aguirre LA, Arnalich F, Maroun-Eid C, Martín-Quirós A, Quintana Díaz M, López-Collazo E. Álvarez E, et al. Among authors: hernandez jimenez e. Front Immunol. 2017 Aug 3;8:915. doi: 10.3389/fimmu.2017.00915. eCollection 2017. Front Immunol. 2017. PMID: 28824640 Free PMC article.
31 results