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Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.
Nead KT, Li A, Wehner MR, Neupane B, Gustafsson S, Butterworth A, Engert JC, Davis AD, Hegele RA, Miller R, den Hoed M, Khaw KT, Kilpeläinen TO, Wareham N, Edwards TL, Hallmans G, Varga TV, Kardia SL, Smith JA, Zhao W, Faul JD, Weir D, Mi J, Xi B, Quinteros SC, Cooper C, Sayer AA, Jameson K, Grøntved A, Fornage M, Sidney S, Hanis CL, Highland HM, Häring HU, Heni M, Lasky-Su J, Weiss ST, Gerhard GS, Still C, Melka MM, Pausova Z, Paus T, Grant SF, Hakonarson H, Price RA, Wang K, Scherag A, Hebebrand J, Hinney A; BioBank Japan, AGEN-BMI, GIANT Consortium; Franks PW, Frayling TM, McCarthy MI, Hirschhorn JN, Loos RJ, Ingelsson E, Gerstein HC, Yusuf S, Beyene J, Anand SS, Meyre D. Nead KT, et al. Among authors: hirschhorn jn. Hum Mol Genet. 2015 Jun 15;24(12):3582-94. doi: 10.1093/hmg/ddv097. Epub 2015 Mar 17. Hum Mol Genet. 2015. PMID: 25784503 Free PMC article. Review.
A comprehensive review of genetic association studies.
Hirschhorn JN, Lohmueller K, Byrne E, Hirschhorn K. Hirschhorn JN, et al. Among authors: hirschhorn k. Genet Med. 2002 Mar-Apr;4(2):45-61. doi: 10.1097/00125817-200203000-00002. Genet Med. 2002. PMID: 11882781 Free article. Review.
5' flanking variants of resistin are associated with obesity.
Engert JC, Vohl MC, Williams SM, Lepage P, Loredo-Osti JC, Faith J, Doré C, Renaud Y, Burtt NP, Villeneuve A, Hirschhorn JN, Altshuler D, Groop LC, Després JP, Gaudet D, Hudson TJ. Engert JC, et al. Among authors: hirschhorn jn. Diabetes. 2002 May;51(5):1629-34. doi: 10.2337/diabetes.51.5.1629. Diabetes. 2002. PMID: 11978666
Assessing the impact of population stratification on genetic association studies.
Freedman ML, Reich D, Penney KL, McDonald GJ, Mignault AA, Patterson N, Gabriel SB, Topol EJ, Smoller JW, Pato CN, Pato MT, Petryshen TL, Kolonel LN, Lander ES, Sklar P, Henderson B, Hirschhorn JN, Altshuler D. Freedman ML, et al. Among authors: hirschhorn jn. Nat Genet. 2004 Apr;36(4):388-93. doi: 10.1038/ng1333. Epub 2004 Mar 28. Nat Genet. 2004. PMID: 15052270
Genetic signatures of strong recent positive selection at the lactase gene.
Bersaglieri T, Sabeti PC, Patterson N, Vanderploeg T, Schaffner SF, Drake JA, Rhodes M, Reich DE, Hirschhorn JN. Bersaglieri T, et al. Among authors: hirschhorn jn. Am J Hum Genet. 2004 Jun;74(6):1111-20. doi: 10.1086/421051. Epub 2004 Apr 26. Am J Hum Genet. 2004. PMID: 15114531 Free PMC article.
Genetics of common forms of obesity: a brief overview.
Lyon HN, Hirschhorn JN. Lyon HN, et al. Among authors: hirschhorn jn. Am J Clin Nutr. 2005 Jul;82(1 Suppl):215S-217S. doi: 10.1093/ajcn/82.1.215S. Am J Clin Nutr. 2005. PMID: 16002823 Free article. Review.
368 results