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Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53.
Kirschner K, Samarajiwa SA, Cairns JM, Menon S, Pérez-Mancera PA, Tomimatsu K, Bermejo-Rodriguez C, Ito Y, Chandra T, Narita M, Lyons SK, Lynch AG, Kimura H, Ohbayashi T, Tavaré S, Narita M. Kirschner K, et al. Among authors: lynch ag. PLoS Genet. 2015 Mar 19;11(3):e1005053. doi: 10.1371/journal.pgen.1005053. eCollection 2015 Mar. PLoS Genet. 2015. PMID: 25790137 Free PMC article.
BayesPeak--an R package for analysing ChIP-seq data.
Cairns J, Spyrou C, Stark R, Smith ML, Lynch AG, Tavaré S. Cairns J, et al. Among authors: lynch ag. Bioinformatics. 2011 Mar 1;27(5):713-4. doi: 10.1093/bioinformatics/btq685. Epub 2011 Jan 17. Bioinformatics. 2011. PMID: 21245054 Free PMC article.
ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium.
Holland DG, Burleigh A, Git A, Goldgraben MA, Perez-Mancera PA, Chin SF, Hurtado A, Bruna A, Ali HR, Greenwood W, Dunning MJ, Samarajiwa S, Menon S, Rueda OM, Lynch AG, McKinney S, Ellis IO, Eaves CJ, Carroll JS, Curtis C, Aparicio S, Caldas C. Holland DG, et al. Among authors: lynch ag. EMBO Mol Med. 2011 Mar;3(3):167-80. doi: 10.1002/emmm.201100122. Epub 2011 Feb 18. EMBO Mol Med. 2011. PMID: 21337521 Free PMC article.
Hidden copy number variation in the HapMap population.
Marioni JC, White M, Tavaré S, Lynch AG. Marioni JC, et al. Among authors: lynch ag. Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10067-72. doi: 10.1073/pnas.0711252105. Epub 2008 Jul 15. Proc Natl Acad Sci U S A. 2008. PMID: 18632583 Free PMC article.
BayesPeak: Bayesian analysis of ChIP-seq data.
Spyrou C, Stark R, Lynch AG, Tavaré S. Spyrou C, et al. Among authors: lynch ag. BMC Bioinformatics. 2009 Sep 21;10:299. doi: 10.1186/1471-2105-10-299. BMC Bioinformatics. 2009. PMID: 19772557 Free PMC article.
151 results