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Targeting a bacterial stress response to enhance antibiotic action.
Lee S, Hinz A, Bauerle E, Angermeyer A, Juhaszova K, Kaneko Y, Singh PK, Manoil C. Lee S, et al. Among authors: singh pk. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14570-5. doi: 10.1073/pnas.0903619106. Epub 2009 Aug 12. Proc Natl Acad Sci U S A. 2009. PMID: 19706543 Free PMC article.
General and condition-specific essential functions of Pseudomonas aeruginosa.
Lee SA, Gallagher LA, Thongdee M, Staudinger BJ, Lippman S, Singh PK, Manoil C. Lee SA, et al. Among authors: singh pk. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5189-94. doi: 10.1073/pnas.1422186112. Epub 2015 Apr 6. Proc Natl Acad Sci U S A. 2015. PMID: 25848053 Free PMC article.
Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs.
Jorth P, Staudinger BJ, Wu X, Hisert KB, Hayden H, Garudathri J, Harding CL, Radey MC, Rezayat A, Bautista G, Berrington WR, Goddard AF, Zheng C, Angermeyer A, Brittnacher MJ, Kitzman J, Shendure J, Fligner CL, Mittler J, Aitken ML, Manoil C, Bruce JE, Yahr TL, Singh PK. Jorth P, et al. Among authors: singh pk. Cell Host Microbe. 2015 Sep 9;18(3):307-19. doi: 10.1016/j.chom.2015.07.006. Epub 2015 Aug 20. Cell Host Microbe. 2015. PMID: 26299432 Free PMC article.
Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange.
Hmelo LR, Borlee BR, Almblad H, Love ME, Randall TE, Tseng BS, Lin C, Irie Y, Storek KM, Yang JJ, Siehnel RJ, Howell PL, Singh PK, Tolker-Nielsen T, Parsek MR, Schweizer HP, Harrison JJ. Hmelo LR, et al. Among authors: singh pk. Nat Protoc. 2015 Nov;10(11):1820-41. doi: 10.1038/nprot.2015.115. Epub 2015 Oct 22. Nat Protoc. 2015. PMID: 26492139 Free PMC article.
Host-Microbe Protein Interactions during Bacterial Infection.
Schweppe DK, Harding C, Chavez JD, Wu X, Ramage E, Singh PK, Manoil C, Bruce JE. Schweppe DK, et al. Among authors: singh pk. Chem Biol. 2015 Nov 19;22(11):1521-1530. doi: 10.1016/j.chembiol.2015.09.015. Epub 2015 Nov 5. Chem Biol. 2015. PMID: 26548613 Free PMC article.
In vivo protein interaction network analysis reveals porin-localized antibiotic inactivation in Acinetobacter baumannii strain AB5075.
Wu X, Chavez JD, Schweppe DK, Zheng C, Weisbrod CR, Eng JK, Murali A, Lee SA, Ramage E, Gallagher LA, Kulasekara HD, Edrozo ME, Kamischke CN, Brittnacher MJ, Miller SI, Singh PK, Manoil C, Bruce JE. Wu X, et al. Among authors: singh pk. Nat Commun. 2016 Nov 11;7:13414. doi: 10.1038/ncomms13414. Nat Commun. 2016. PMID: 27834373 Free PMC article.
2,327 results