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Activation of necroptosis in multiple sclerosis.
Ofengeim D, Ito Y, Najafov A, Zhang Y, Shan B, DeWitt JP, Ye J, Zhang X, Chang A, Vakifahmetoglu-Norberg H, Geng J, Py B, Zhou W, Amin P, Berlink Lima J, Qi C, Yu Q, Trapp B, Yuan J. Ofengeim D, et al. Among authors: dewitt jp. Cell Rep. 2015 Mar 24;10(11):1836-49. doi: 10.1016/j.celrep.2015.02.051. Cell Rep. 2015. PMID: 25801023 Free PMC article.
RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.
Ito Y, Ofengeim D, Najafov A, Das S, Saberi S, Li Y, Hitomi J, Zhu H, Chen H, Mayo L, Geng J, Amin P, DeWitt JP, Mookhtiar AK, Florez M, Ouchida AT, Fan JB, Pasparakis M, Kelliher MA, Ravits J, Yuan J. Ito Y, et al. Among authors: dewitt jp. Science. 2016 Aug 5;353(6299):603-8. doi: 10.1126/science.aaf6803. Science. 2016. PMID: 27493188 Free PMC article.
RIPK1 mediates a disease-associated microglial response in Alzheimer's disease.
Ofengeim D, Mazzitelli S, Ito Y, DeWitt JP, Mifflin L, Zou C, Das S, Adiconis X, Chen H, Zhu H, Kelliher MA, Levin JZ, Yuan J. Ofengeim D, et al. Among authors: dewitt jp. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8788-E8797. doi: 10.1073/pnas.1714175114. Epub 2017 Sep 13. Proc Natl Acad Sci U S A. 2017. PMID: 28904096 Free PMC article.
Cancer therapy in the necroptosis era.
Su Z, Yang Z, Xie L, DeWitt JP, Chen Y. Su Z, et al. Among authors: dewitt jp. Cell Death Differ. 2016 May;23(5):748-56. doi: 10.1038/cdd.2016.8. Epub 2016 Feb 26. Cell Death Differ. 2016. PMID: 26915291 Free PMC article. Review.
Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy.
Yang Z, Su Z, DeWitt JP, Xie L, Chen Y, Li X, Han L, Li D, Xia J, Zhang Y, Yang Y, Jin C, Zhang J, Li S, Li K, Zhang Z, Qu X, He Z, Chen Y, Shen Y, Ren M, Yuan Z. Yang Z, et al. Among authors: dewitt jp. EBioMedicine. 2017 May;19:49-59. doi: 10.1016/j.ebiom.2017.04.017. Epub 2017 Apr 11. EBioMedicine. 2017. PMID: 28454732 Free PMC article.
16 results