Najafov A - Search Results

1

Activation of necroptosis in multiple sclerosis.

Ofengeim D, Ito Y, Najafov A, Zhang Y, Shan B, DeWitt JP, Ye J, Zhang X, Chang A, Vakifahmetoglu-Norberg H, Geng J, Py B, Zhou W, Amin P, Berlink Lima J, Qi C, Yu Q, Trapp B, Yuan J. Ofengeim D, et al. Among authors: najafov a. Cell Rep. 2015 Mar 24;10(11):1836-49. doi: 10.1016/j.celrep.2015.02.051. Cell Rep. 2015. PMID: 25801023 Free PMC article.

2

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.

Ito Y, Ofengeim D, Najafov A, Das S, Saberi S, Li Y, Hitomi J, Zhu H, Chen H, Mayo L, Geng J, Amin P, DeWitt JP, Mookhtiar AK, Florez M, Ouchida AT, Fan JB, Pasparakis M, Kelliher MA, Ravits J, Yuan J. Ito Y, et al. Among authors: najafov a. Science. 2016 Aug 5;353(6299):603-8. doi: 10.1126/science.aaf6803. Science. 2016. PMID: 27493188 Free PMC article.

3

Roles of Caspases in Necrotic Cell Death.

Yuan J, Najafov A, Py BF. Yuan J, et al. Among authors: najafov a. Cell. 2016 Dec 15;167(7):1693-1704. doi: 10.1016/j.cell.2016.11.047. Cell. 2016. PMID: 27984721 Free PMC article. Review.

4

Necroptosis and Cancer.

Najafov A, Chen H, Yuan J. Najafov A, et al. Trends Cancer. 2017 Apr;3(4):294-301. doi: 10.1016/j.trecan.2017.03.002. Trends Cancer. 2017. PMID: 28451648 Free PMC article.

5

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.

Geng J, Ito Y, Shi L, Amin P, Chu J, Ouchida AT, Mookhtiar AK, Zhao H, Xu D, Shan B, Najafov A, Gao G, Akira S, Yuan J. Geng J, et al. Among authors: najafov a. Nat Commun. 2017 Aug 25;8(1):359. doi: 10.1038/s41467-017-00406-w. Nat Commun. 2017. PMID: 28842570 Free PMC article.

6

Necroptosis in development and diseases.

Shan B, Pan H, Najafov A, Yuan J. Shan B, et al. Among authors: najafov a. Genes Dev. 2018 Mar 1;32(5-6):327-340. doi: 10.1101/gad.312561.118. Genes Dev. 2018. PMID: 29593066 Free PMC article. Review.

7

TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL.

Najafov A, Mookhtiar AK, Luu HS, Ordureau A, Pan H, Amin PP, Li Y, Lu Q, Yuan J. Najafov A, et al. Mol Cell. 2019 Aug 8;75(3):457-468.e4. doi: 10.1016/j.molcel.2019.05.022. Epub 2019 Jun 20. Mol Cell. 2019. PMID: 31230815 Free article.

8

ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC.

Dziedzic SA, Su Z, Jean Barrett V, Najafov A, Mookhtiar AK, Amin P, Pan H, Sun L, Zhu H, Ma A, Abbott DW, Yuan J. Dziedzic SA, et al. Among authors: najafov a. Nat Cell Biol. 2018 Jan;20(1):58-68. doi: 10.1038/s41556-017-0003-1. Epub 2017 Dec 4. Nat Cell Biol. 2018. PMID: 29203883 Free PMC article.

9

Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis.

Amin P, Florez M, Najafov A, Pan H, Geng J, Ofengeim D, Dziedzic SA, Wang H, Barrett VJ, Ito Y, LaVoie MJ, Yuan J. Amin P, et al. Among authors: najafov a. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5944-E5953. doi: 10.1073/pnas.1806973115. Epub 2018 Jun 11. Proc Natl Acad Sci U S A. 2018. PMID: 29891719 Free PMC article.

10

Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death.

Ouchida AT, Li Y, Geng J, Najafov A, Ofengeim D, Sun X, Yu Q, Yuan J. Ouchida AT, et al. Among authors: najafov a. Cell Death Dis. 2018 Jan 26;9(2):138. doi: 10.1038/s41419-017-0170-9. Cell Death Dis. 2018. PMID: 29374185 Free PMC article.

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