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Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes.
Tersey SA, Bolanis E, Holman TR, Maloney DJ, Nadler JL, Mirmira RG. Tersey SA, et al. Among authors: nadler jl. Mol Endocrinol. 2015 Jun;29(6):791-800. doi: 10.1210/me.2015-1041. Epub 2015 Mar 24. Mol Endocrinol. 2015. PMID: 25803446 Free PMC article. Review.
Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development.
Green-Mitchell SM, Tersey SA, Cole BK, Ma K, Kuhn NS, Cunningham TD, Maybee NA, Chakrabarti SK, McDuffie M, Taylor-Fishwick DA, Mirmira RG, Nadler JL, Morris MA. Green-Mitchell SM, et al. Among authors: nadler jl. PLoS One. 2013;8(2):e56763. doi: 10.1371/journal.pone.0056763. Epub 2013 Feb 21. PLoS One. 2013. PMID: 23437231 Free PMC article.
Inhibition of 12/15-Lipoxygenase Protects Against β-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes.
Hernandez-Perez M, Chopra G, Fine J, Conteh AM, Anderson RM, Linnemann AK, Benjamin C, Nelson JB, Benninger KS, Nadler JL, Maloney DJ, Tersey SA, Mirmira RG. Hernandez-Perez M, et al. Among authors: nadler jl. Diabetes. 2017 Nov;66(11):2875-2887. doi: 10.2337/db17-0215. Epub 2017 Aug 25. Diabetes. 2017. PMID: 28842399 Free PMC article.
Role of the 12-lipoxygenase pathway in diabetes pathogenesis and complications.
Dobrian AD, Morris MA, Taylor-Fishwick DA, Holman TR, Imai Y, Mirmira RG, Nadler JL. Dobrian AD, et al. Among authors: nadler jl. Pharmacol Ther. 2019 Mar;195:100-110. doi: 10.1016/j.pharmthera.2018.10.010. Epub 2018 Oct 19. Pharmacol Ther. 2019. PMID: 30347209 Free PMC article. Review.
258 results