Scharfman HE - Search Results

1

Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline.

Cho KO, Lybrand ZR, Ito N, Brulet R, Tafacory F, Zhang L, Good L, Ure K, Kernie SG, Birnbaum SG, Scharfman HE, Eisch AJ, Hsieh J. Cho KO, et al. Among authors: scharfman he. Nat Commun. 2015 Mar 26;6:6606. doi: 10.1038/ncomms7606. Nat Commun. 2015. PMID: 25808087 Free PMC article.

2

Postnatal neurogenesis as a therapeutic target in temporal lobe epilepsy.

Scharfman HE, McCloskey DP. Scharfman HE, et al. Epilepsy Res. 2009 Aug;85(2-3):150-61. doi: 10.1016/j.eplepsyres.2009.03.006. Epub 2009 Apr 14. Epilepsy Res. 2009. PMID: 19369038 Free PMC article. Review.

3

Spike-wave discharges in adult Sprague-Dawley rats and their implications for animal models of temporal lobe epilepsy.

Pearce PS, Friedman D, Lafrancois JJ, Iyengar SS, Fenton AA, Maclusky NJ, Scharfman HE. Pearce PS, et al. Among authors: scharfman he. Epilepsy Behav. 2014 Mar;32:121-31. doi: 10.1016/j.yebeh.2014.01.004. Epub 2014 Feb 15. Epilepsy Behav. 2014. PMID: 24534480 Free PMC article. Review.

4

Androgen Modulation of Hippocampal Structure and Function.

Atwi S, McMahon D, Scharfman H, MacLusky NJ. Atwi S, et al. Neuroscientist. 2016 Feb;22(1):46-60. doi: 10.1177/1073858414558065. Epub 2014 Nov 21. Neuroscientist. 2016. PMID: 25416742 Free PMC article. Review.

5

Suppression of adult neurogenesis increases the acute effects of kainic acid.

Iyengar SS, LaFrancois JJ, Friedman D, Drew LJ, Denny CA, Burghardt NS, Wu MV, Hsieh J, Hen R, Scharfman HE. Iyengar SS, et al. Among authors: scharfman he. Exp Neurol. 2015 Feb;264:135-49. doi: 10.1016/j.expneurol.2014.11.009. Epub 2014 Dec 2. Exp Neurol. 2015. PMID: 25476494 Free PMC article.

6

The enigmatic mossy cell of the dentate gyrus.

Scharfman HE. Scharfman HE. Nat Rev Neurosci. 2016 Sep;17(9):562-75. doi: 10.1038/nrn.2016.87. Epub 2016 Jul 28. Nat Rev Neurosci. 2016. PMID: 27466143 Free PMC article. Review.

7

Increased gyrification and aberrant adult neurogenesis of the dentate gyrus in adult rats.

Magagna-Poveda A, Moretto JN, Scharfman HE. Magagna-Poveda A, et al. Among authors: scharfman he. Brain Struct Funct. 2017 Dec;222(9):4219-4237. doi: 10.1007/s00429-017-1457-4. Epub 2017 Jun 27. Brain Struct Funct. 2017. PMID: 28656372 Free PMC article.

8

Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits.

You JC, Muralidharan K, Park JW, Petrof I, Pyfer MS, Corbett BF, LaFrancois JJ, Zheng Y, Zhang X, Mohila CA, Yoshor D, Rissman RA, Nestler EJ, Scharfman HE, Chin J. You JC, et al. Among authors: scharfman he. Nat Med. 2017 Nov;23(11):1377-1383. doi: 10.1038/nm.4413. Epub 2017 Oct 16. Nat Med. 2017. PMID: 29035369 Free PMC article.

9

Adult neurogenesis in the mouse dentate gyrus protects the hippocampus from neuronal injury following severe seizures.

Jain S, LaFrancois JJ, Botterill JJ, Alcantara-Gonzalez D, Scharfman HE. Jain S, et al. Among authors: scharfman he. Hippocampus. 2019 Aug;29(8):683-709. doi: 10.1002/hipo.23062. Epub 2019 Jan 23. Hippocampus. 2019. PMID: 30672046 Free PMC article.

10

Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy.

Whitebirch AC, LaFrancois JJ, Jain S, Leary P, Santoro B, Siegelbaum SA, Scharfman HE. Whitebirch AC, et al. Among authors: scharfman he. Neuron. 2022 Oct 5;110(19):3121-3138.e8. doi: 10.1016/j.neuron.2022.07.020. Epub 2022 Aug 19. Neuron. 2022. PMID: 35987207 Free PMC article.

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