Wempe MF - Search Results

1

Promiscuous actions of small molecule inhibitors of the protein kinase D-class IIa HDAC axis in striated muscle.

Lemon DD, Harrison BC, Horn TR, Stratton MS, Ferguson BS, Wempe MF, McKinsey TA. Lemon DD, et al. Among authors: wempe mf. FEBS Lett. 2015 Apr 28;589(10):1080-8. doi: 10.1016/j.febslet.2015.03.017. Epub 2015 Mar 25. FEBS Lett. 2015. PMID: 25816750 Free PMC article.

2

Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy.

Ferguson BS, Harrison BC, Jeong MY, Reid BG, Wempe MF, Wagner FF, Holson EB, McKinsey TA. Ferguson BS, et al. Among authors: wempe mf. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9806-11. doi: 10.1073/pnas.1301509110. Epub 2013 May 29. Proc Natl Acad Sci U S A. 2013. PMID: 23720316 Free PMC article.

3

Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts.

Schuetze KB, Stratton MS, Blakeslee WW, Wempe MF, Wagner FF, Holson EB, Kuo YM, Andrews AJ, Gilbert TM, Hooker JM, McKinsey TA. Schuetze KB, et al. Among authors: wempe mf. J Pharmacol Exp Ther. 2017 Apr;361(1):140-150. doi: 10.1124/jpet.116.237701. Epub 2017 Feb 7. J Pharmacol Exp Ther. 2017. PMID: 28174211 Free PMC article.

4

Synthesis of novel Ral inhibitors: An in vitro and in vivo study.

Yan C, Theodorescu D, Miller B, Kumar A, Kumar V, Ross D, Wempe MF. Yan C, et al. Among authors: wempe mf. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5815-5818. doi: 10.1016/j.bmcl.2016.10.021. Epub 2016 Oct 12. Bioorg Med Chem Lett. 2016. PMID: 27825764 Free PMC article.

5

Procyanidin B2 3,3″-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK.

Kumar R, Deep G, Wempe MF, Surek J, Kumar A, Agarwal R, Agarwal C. Kumar R, et al. Among authors: wempe mf. Mol Carcinog. 2018 Jan;57(1):57-69. doi: 10.1002/mc.22731. Epub 2017 Sep 22. Mol Carcinog. 2018. PMID: 28876465 Free PMC article.

6

ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.

Gregory MA, D'Alessandro A, Alvarez-Calderon F, Kim J, Nemkov T, Adane B, Rozhok AI, Kumar A, Kumar V, Pollyea DA, Wempe MF, Jordan CT, Serkova NJ, Tan AC, Hansen KC, DeGregori J. Gregory MA, et al. Among authors: wempe mf. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6669-E6678. doi: 10.1073/pnas.1603876113. Epub 2016 Oct 10. Proc Natl Acad Sci U S A. 2016. PMID: 27791036 Free PMC article.

7

Developing potent human uric acid transporter 1 (hURAT1) inhibitors.

Wempe MF, Jutabha P, Quade B, Iwen TJ, Frick MM, Ross IR, Rice PJ, Anzai N, Endou H. Wempe MF, et al. J Med Chem. 2011 Apr 28;54(8):2701-13. doi: 10.1021/jm1015022. Epub 2011 Mar 30. J Med Chem. 2011. PMID: 21449597 Free PMC article.

8

A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells.

Matheson CJ, Venkataraman S, Amani V, Harris PS, Backos DS, Donson AM, Wempe MF, Foreman NK, Vibhakar R, Reigan P. Matheson CJ, et al. Among authors: wempe mf. ACS Chem Biol. 2016 Apr 15;11(4):921-30. doi: 10.1021/acschembio.5b00725. Epub 2016 Jan 8. ACS Chem Biol. 2016. PMID: 26745241

9

Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells.

Kaur M, Deep G, Jain AK, Raina K, Agarwal C, Wempe MF, Agarwal R. Kaur M, et al. Among authors: wempe mf. Carcinogenesis. 2013 Jul;34(7):1585-92. doi: 10.1093/carcin/bgt081. Epub 2013 Mar 8. Carcinogenesis. 2013. PMID: 23475945 Free PMC article.

10

New Insights into Ion Channels: Predicting hERG-Drug Interactions.

Wempe MF. Wempe MF. Int J Mol Sci. 2022 Sep 14;23(18):10732. doi: 10.3390/ijms231810732. Int J Mol Sci. 2022. PMID: 36142644 Free PMC article.

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