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A homogenizing process of selection has maintained an "ultra-slow" acetylation NAT2 variant in humans.
Hum Biol. 2014 Summer;86(3):185-214. doi: 10.13110/humanbiology.86.3.0185.
Hum Biol. 2014.
PMID: 25836746
Balancing immunity and tolerance: genetic footprint of natural selection in the transcriptional regulatory region of HLA-G.
Gineau L, Luisi P, Castelli EC, Milet J, Courtin D, Cagnin N, Patillon B, Laayouni H, Moreau P, Donadi EA, Garcia A, Sabbagh A.
Gineau L, et al. Among authors: patillon b.
Genes Immun. 2015 Jan-Feb;16(1):57-70. doi: 10.1038/gene.2014.63. Epub 2014 Nov 13.
Genes Immun. 2015.
PMID: 25393930
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Positive selection in the chromosome 16 VKORC1 genomic region has contributed to the variability of anticoagulant response in humans.
Patillon B, Luisi P, Blanché H, Patin E, Cann HM, Génin E, Sabbagh A.
Patillon B, et al.
PLoS One. 2012;7(12):e53049. doi: 10.1371/journal.pone.0053049. Epub 2012 Dec 28.
PLoS One. 2012.
PMID: 23285254
Free PMC article.
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MDM2 as a modifier gene in retinoblastoma.
Castéra L, Sabbagh A, Dehainault C, Michaux D, Mansuet-Lupo A, Patillon B, Lamar E, Aerts I, Lumbroso-Le Rouic L, Couturier J, Stoppa-Lyonnet D, Gauthier-Villars M, Houdayer C.
Castéra L, et al. Among authors: patillon b.
J Natl Cancer Inst. 2010 Dec 1;102(23):1805-8. doi: 10.1093/jnci/djq416. Epub 2010 Nov 4.
J Natl Cancer Inst. 2010.
PMID: 21051655
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