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Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress.
Mercado N, Thimmulappa R, Thomas CM, Fenwick PS, Chana KK, Donnelly LE, Biswal S, Ito K, Barnes PJ. Mercado N, et al. Among authors: donnelly le. Biochem Biophys Res Commun. 2011 Mar 11;406(2):292-8. doi: 10.1016/j.bbrc.2011.02.035. Epub 2011 Feb 12. Biochem Biophys Res Commun. 2011. PMID: 21320471 Free PMC article.
Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes.
Smith SJ, Cieslinski LB, Newton R, Donnelly LE, Fenwick PS, Nicholson AG, Barnes PJ, Barnette MS, Giembycz MA. Smith SJ, et al. Among authors: donnelly le. Mol Pharmacol. 2004 Dec;66(6):1679-89. doi: 10.1124/mol.104.002246. Epub 2004 Sep 15. Mol Pharmacol. 2004. PMID: 15371556
129 results