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Toxicity profile and treatment delays in NOPHO ALL2008-comparing adults and children with Philadelphia chromosome-negative acute lymphoblastic leukemia.
Toft N, Birgens H, Abrahamsson J, Griškevičius L, Hallböök H, Heyman M, Klausen TW, Jónsson ÓG, Palk K, Pruunsild K, Quist-Paulsen P, Vaitkeviciene G, Vettenranta K, Asberg A, Helt LR, Frandsen T, Schmiegelow K. Toft N, et al. Among authors: helt lr. Eur J Haematol. 2016 Feb;96(2):160-9. doi: 10.1111/ejh.12562. Epub 2015 Apr 24. Eur J Haematol. 2016. PMID: 25867866
Comparing osteonecrosis clinical phenotype, timing, and risk factors in children and young adults treated for acute lymphoblastic leukemia.
Mogensen SS, Harila-Saari A, Mäkitie O, Myrberg IH, Niinimäki R, Vestli A, Hafsteinsdottir S, Griškevicius L, Saks K, Hallböök H, Retpen J, Helt LR, Toft N, Schmiegelow K, Frandsen TL; Nordic Society of Paediatric Haematology and Oncology (NOPHO) group. Mogensen SS, et al. Among authors: helt lr. Pediatr Blood Cancer. 2018 Oct;65(10):e27300. doi: 10.1002/pbc.27300. Epub 2018 Jun 26. Pediatr Blood Cancer. 2018. PMID: 29943905
TPMT polymorphisms and minimal residual disease after 6-mercaptopurine post-remission consolidation therapy of childhood acute lymphoblastic leukaemia.
Dreisig K, Brünner ED, Marquart HV, Helt LR, Nersting J, Frandsen TL, Jonsson OG, Taskinen M, Vaitkeviciene G, Lund B, Abrahamsson J, Lepik K, Schmiegelow K. Dreisig K, et al. Among authors: helt lr. Pediatr Hematol Oncol. 2021 Apr;38(3):227-238. doi: 10.1080/08880018.2020.1842570. Epub 2020 Nov 18. Pediatr Hematol Oncol. 2021. PMID: 33205673 Clinical Trial.
Asparaginase-associated pancreatitis: a study on phenotype and genotype in the NOPHO ALL2008 protocol.
Wolthers BO, Frandsen TL, Abrahamsson J, Albertsen BK, Helt LR, Heyman M, Jónsson ÓG, Kõrgvee LT, Lund B, Raja RA, Rasmussen KK, Taskinen M, Tulstrup M, Vaitkevičienė GE, Yadav R, Gupta R, Schmiegelow K. Wolthers BO, et al. Among authors: helt lr. Leukemia. 2017 Feb;31(2):325-332. doi: 10.1038/leu.2016.203. Epub 2016 Jul 25. Leukemia. 2017. PMID: 27451978
Complying with the European Clinical Trials directive while surviving the administrative pressure - an alternative approach to toxicity registration in a cancer trial.
Frandsen TL, Heyman M, Abrahamsson J, Vettenranta K, Åsberg A, Vaitkeviciene G, Pruunsild K, Toft N, Birgens H, Hallböök H, Quist-Paulsen P, Griškevičius L, Helt L, Hansen BV, Schmiegelow K. Frandsen TL, et al. Eur J Cancer. 2014 Jan;50(2):251-9. doi: 10.1016/j.ejca.2013.09.027. Epub 2013 Nov 11. Eur J Cancer. 2014. PMID: 24231337
Cost-effective multiplexing before capture allows screening of 25 000 clinically relevant SNPs in childhood acute lymphoblastic leukemia.
Wesolowska A, Dalgaard MD, Borst L, Gautier L, Bak M, Weinhold N, Nielsen BF, Helt LR, Audouze K, Nersting J, Tommerup N, Brunak S, Sicheritz-Ponten T, Leffers H, Schmiegelow K, Gupta R. Wesolowska A, et al. Among authors: helt lr. Leukemia. 2011 Jun;25(6):1001-6. doi: 10.1038/leu.2011.32. Epub 2011 Mar 18. Leukemia. 2011. PMID: 21415851