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An analysis of gene expression in PTSD implicates genes involved in the glucocorticoid receptor pathway and neural responses to stress.
Logue MW, Smith AK, Baldwin C, Wolf EJ, Guffanti G, Ratanatharathorn A, Stone A, Schichman SA, Humphries D, Binder EB, Arloth J, Menke A, Uddin M, Wildman D, Galea S, Aiello AE, Koenen KC, Miller MW. Logue MW, et al. Among authors: smith ak. Psychoneuroendocrinology. 2015 Jul;57:1-13. doi: 10.1016/j.psyneuen.2015.03.016. Epub 2015 Mar 24. Psychoneuroendocrinology. 2015. PMID: 25867994 Free PMC article.
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor.
Ressler KJ, Mercer KB, Bradley B, Jovanovic T, Mahan A, Kerley K, Norrholm SD, Kilaru V, Smith AK, Myers AJ, Ramirez M, Engel A, Hammack SE, Toufexis D, Braas KM, Binder EB, May V. Ressler KJ, et al. Among authors: smith ak. Nature. 2011 Feb 24;470(7335):492-7. doi: 10.1038/nature09856. Nature. 2011. PMID: 21350482 Free PMC article.
Sex dependent influence of a functional polymorphism in steroid 5-α-reductase type 2 (SRD5A2) on post-traumatic stress symptoms.
Gillespie CF, Almli LM, Smith AK, Bradley B, Kerley K, Crain DF, Mercer KB, Weiss T, Phifer J, Tang Y, Cubells JF, Binder EB, Conneely KN, Ressler KJ. Gillespie CF, et al. Among authors: smith ak. Am J Med Genet B Neuropsychiatr Genet. 2013 Apr;162B(3):283-292. doi: 10.1002/ajmg.b.32147. Epub 2013 Mar 15. Am J Med Genet B Neuropsychiatr Genet. 2013. PMID: 23505265 Free PMC article.
Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder.
Norrholm SD, Jovanovic T, Smith AK, Binder E, Klengel T, Conneely K, Mercer KB, Davis JS, Kerley K, Winkler J, Gillespie CF, Bradley B, Ressler KJ. Norrholm SD, et al. Among authors: smith ak. Front Behav Neurosci. 2013 Apr 10;7:30. doi: 10.3389/fnbeh.2013.00030. eCollection 2013. Front Behav Neurosci. 2013. PMID: 23596403 Free PMC article.
Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder.
Mehta D, Klengel T, Conneely KN, Smith AK, Altmann A, Pace TW, Rex-Haffner M, Loeschner A, Gonik M, Mercer KB, Bradley B, Müller-Myhsok B, Ressler KJ, Binder EB. Mehta D, et al. Among authors: smith ak. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8302-7. doi: 10.1073/pnas.1217750110. Epub 2013 Apr 29. Proc Natl Acad Sci U S A. 2013. PMID: 23630272 Free PMC article.
Accounting for population stratification in DNA methylation studies.
Barfield RT, Almli LM, Kilaru V, Smith AK, Mercer KB, Duncan R, Klengel T, Mehta D, Binder EB, Epstein MP, Ressler KJ, Conneely KN. Barfield RT, et al. Among authors: smith ak. Genet Epidemiol. 2014 Apr;38(3):231-41. doi: 10.1002/gepi.21789. Epub 2014 Jan 29. Genet Epidemiol. 2014. PMID: 24478250 Free PMC article.
643 results