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A common sugar-nucleotide-mediated mechanism of inhibition of (glycosamino)glycan biosynthesis, as evidenced by 6F-GalNAc (Ac3).
van Wijk XM, Lawrence R, Thijssen VL, van den Broek SA, Troost R, van Scherpenzeel M, Naidu N, Oosterhof A, Griffioen AW, Lefeber DJ, van Delft FL, van Kuppevelt TH. van Wijk XM, et al. Among authors: griffioen aw. FASEB J. 2015 Jul;29(7):2993-3002. doi: 10.1096/fj.14-264226. Epub 2015 Apr 13. FASEB J. 2015. PMID: 25868729 Free PMC article.
High-grade clear cell renal cell carcinoma has a higher angiogenic activity than low-grade renal cell carcinoma based on histomorphological quantification and qRT-PCR mRNA expression profile.
Baldewijns MM, Thijssen VL, Van den Eynden GG, Van Laere SJ, Bluekens AM, Roskams T, van Poppel H, De Bruïne AP, Griffioen AW, Vermeulen PB. Baldewijns MM, et al. Among authors: griffioen aw. Br J Cancer. 2007 Jun 18;96(12):1888-95. doi: 10.1038/sj.bjc.6603796. Epub 2007 May 15. Br J Cancer. 2007. PMID: 17505508 Free PMC article.
Tumor cells secrete galectin-1 to enhance endothelial cell activity.
Thijssen VL, Barkan B, Shoji H, Aries IM, Mathieu V, Deltour L, Hackeng TM, Kiss R, Kloog Y, Poirier F, Griffioen AW. Thijssen VL, et al. Among authors: griffioen aw. Cancer Res. 2010 Aug 1;70(15):6216-24. doi: 10.1158/0008-5472.CAN-09-4150. Epub 2010 Jul 20. Cancer Res. 2010. PMID: 20647324
Combining angiogenesis inhibition and radiotherapy: a double-edged sword.
Kleibeuker EA, Griffioen AW, Verheul HM, Slotman BJ, Thijssen VL. Kleibeuker EA, et al. Among authors: griffioen aw. Drug Resist Updat. 2012 Jun;15(3):173-82. doi: 10.1016/j.drup.2012.04.002. Epub 2012 May 4. Drug Resist Updat. 2012. PMID: 22561672 Review.
295 results