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HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-κB Signaling and Promotes Tissue Damage-Associated Tumorigenesis.
Janeckova L, Pospichalova V, Fafilek B, Vojtechova M, Tureckova J, Dobes J, Dubuissez M, Leprince D, Baloghova N, Horazna M, Hlavata A, Stancikova J, Sloncova E, Galuskova K, Strnad H, Korinek V. Janeckova L, et al. Among authors: leprince d. Mol Cancer Res. 2015 Jul;13(7):1139-48. doi: 10.1158/1541-7786.MCR-15-0033. Epub 2015 May 1. Mol Cancer Res. 2015. PMID: 25934696
Generation of two modified mouse alleles of the Hic1 tumor suppressor gene.
Pospichalova V, Tureckova J, Fafilek B, Vojtechova M, Krausova M, Lukas J, Sloncova E, Takacova S, Divoky V, Leprince D, Plachy J, Korinek V. Pospichalova V, et al. Among authors: leprince d. Genesis. 2011 Mar;49(3):142-51. doi: 10.1002/dvg.20719. Genesis. 2011. PMID: 21309068
HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs).
Paget S, Dubuissez M, Dehennaut V, Nassour J, Harmon BT, Spruyt N, Loison I, Abbadie C, Rood BR, Leprince D. Paget S, et al. Among authors: leprince d. Oncotarget. 2017 Jan 10;8(2):2916-2935. doi: 10.18632/oncotarget.13807. Oncotarget. 2017. PMID: 27935866 Free PMC article.
HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression.
Dubuissez M, Paget S, Abdelfettah S, Spruyt N, Dehennaut V, Boulay G, Loison I, de Schutter C, Rood BR, Duterque-Coquillaud M, Leroy X, Leprince D. Dubuissez M, et al. Among authors: leprince d. Oncotarget. 2020 Nov 10;11(45):4138-4154. doi: 10.18632/oncotarget.27786. eCollection 2020 Nov 10. Oncotarget. 2020. PMID: 33227080 Free PMC article.
102 results