Lehto T - Search Results

1

PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo.

Veiman KL, Künnapuu K, Lehto T, Kiisholts K, Pärn K, Langel Ü, Kurrikoff K. Veiman KL, et al. Among authors: lehto t. J Control Release. 2015 Jul 10;209:238-47. doi: 10.1016/j.jconrel.2015.04.038. Epub 2015 Apr 30. J Control Release. 2015. PMID: 25935707 Free article.

2

PepFect14 peptide vector for efficient gene delivery in cell cultures.

Veiman KL, Mäger I, Ezzat K, Margus H, Lehto T, Langel K, Kurrikoff K, Arukuusk P, Suhorutšenko J, Padari K, Pooga M, Lehto T, Langel Ü. Veiman KL, et al. Among authors: lehto t. Mol Pharm. 2013 Jan 7;10(1):199-210. doi: 10.1021/mp3003557. Epub 2012 Dec 14. Mol Pharm. 2013. PMID: 23186360

3

Effective in vivo gene delivery with reduced toxicity, achieved by charge and fatty acid -modified cell penetrating peptide.

Kurrikoff K, Veiman KL, Künnapuu K, Peets EM, Lehto T, Pärnaste L, Arukuusk P, Langel Ü. Kurrikoff K, et al. Among authors: lehto t. Sci Rep. 2017 Dec 6;7(1):17056. doi: 10.1038/s41598-017-17316-y. Sci Rep. 2017. PMID: 29213085 Free PMC article.

4

Saturated Fatty Acid Analogues of Cell-Penetrating Peptide PepFect14: Role of Fatty Acid Modification in Complexation and Delivery of Splice-Correcting Oligonucleotides.

Lehto T, Vasconcelos L, Margus H, Figueroa R, Pooga M, Hällbrink M, Langel Ü. Lehto T, et al. Bioconjug Chem. 2017 Mar 15;28(3):782-792. doi: 10.1021/acs.bioconjchem.6b00680. Epub 2017 Mar 2. Bioconjug Chem. 2017. PMID: 28209057

5

Intracellular delivery of therapeutic antisense oligonucleotides targeting mRNA coding mitochondrial proteins by cell-penetrating peptides.

Cerrato CP, Kivijärvi T, Tozzi R, Lehto T, Gestin M, Langel Ü. Cerrato CP, et al. Among authors: lehto t. J Mater Chem B. 2020 Dec 21;8(47):10825-10836. doi: 10.1039/d0tb01106a. Epub 2020 Nov 11. J Mater Chem B. 2020. PMID: 33174901

6

Simultaneous membrane interaction of amphipathic peptide monomers, self-aggregates and cargo complexes detected by fluorescence correlation spectroscopy.

Vasconcelos L, Lehto T, Madani F, Radoi V, Hällbrink M, Vukojević V, Langel Ü. Vasconcelos L, et al. Among authors: lehto t. Biochim Biophys Acta Biomembr. 2018 Feb;1860(2):491-504. doi: 10.1016/j.bbamem.2017.09.024. Epub 2017 Sep 28. Biochim Biophys Acta Biomembr. 2018. PMID: 28962904 Free article.

7

Peptide-based vectors: recent developments.

Cerrato CP, Lehto T, Langel Ü. Cerrato CP, et al. Among authors: lehto t. Biomol Concepts. 2014 Dec;5(6):479-88. doi: 10.1515/bmc-2014-0024. Biomol Concepts. 2014. PMID: 25429600 Free article. Review.

8

Astrocytes promote ethanol-induced enhancement of intracellular Ca²⁺ signals through intercellular communication with neurons.

Kim HB, Morris J, Miyashiro K, Lehto T, Langel Ü, Eberwine J, Sul JY. Kim HB, et al. Among authors: lehto t. iScience. 2021 Apr 17;24(5):102436. doi: 10.1016/j.isci.2021.102436. eCollection 2021 May 21. iScience. 2021. PMID: 33997707 Free PMC article.

9

Efficient Peptide-Mediated In Vitro Delivery of Cas9 RNP.

Gustafsson O, Rädler J, Roudi S, Lehto T, Hällbrink M, Lehto T, Gupta D, Andaloussi SE, Nordin JZ. Gustafsson O, et al. Among authors: lehto t. Pharmaceutics. 2021 Jun 14;13(6):878. doi: 10.3390/pharmaceutics13060878. Pharmaceutics. 2021. PMID: 34198625 Free PMC article.

10

MRI-Targeted Prostate Biopsy Introduces Grade Inflation and Overtreatment.

Batouche AO, Czeizler E, Lehto TP, Erickson A, Shadbahr T, Laajala TD, Pohjonen J, Vickers AJ, Mirtti T, Rannikko AS. Batouche AO, et al. Among authors: lehto tp. medRxiv [Preprint]. 2024 Jan 10:2024.01.10.24300922. doi: 10.1101/2024.01.10.24300922. medRxiv. 2024. PMID: 38260466 Free PMC article. Preprint.

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