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Determinants of gliadin-specific T cell selection in celiac disease.
Petersen J, van Bergen J, Loh KL, Kooy-Winkelaar Y, Beringer DX, Thompson A, Bakker SF, Mulder CJ, Ladell K, McLaren JE, Price DA, Rossjohn J, Reid HH, Koning F. Petersen J, et al. Among authors: loh kl. J Immunol. 2015 Jun 15;194(12):6112-22. doi: 10.4049/jimmunol.1500161. Epub 2015 May 6. J Immunol. 2015. PMID: 25948817
Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease.
Broughton SE, Petersen J, Theodossis A, Scally SW, Loh KL, Thompson A, van Bergen J, Kooy-Winkelaar Y, Henderson KN, Beddoe T, Tye-Din JA, Mannering SI, Purcell AW, McCluskey J, Anderson RP, Koning F, Reid HH, Rossjohn J. Broughton SE, et al. Among authors: loh kl. Immunity. 2012 Oct 19;37(4):611-21. doi: 10.1016/j.immuni.2012.07.013. Epub 2012 Oct 11. Immunity. 2012. PMID: 23063329 Free article.
A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis.
Scally SW, Petersen J, Law SC, Dudek NL, Nel HJ, Loh KL, Wijeyewickrema LC, Eckle SB, van Heemst J, Pike RN, McCluskey J, Toes RE, La Gruta NL, Purcell AW, Reid HH, Thomas R, Rossjohn J. Scally SW, et al. Among authors: loh kl. J Exp Med. 2013 Nov 18;210(12):2569-82. doi: 10.1084/jem.20131241. Epub 2013 Nov 4. J Exp Med. 2013. PMID: 24190431 Free PMC article.
T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.
Petersen J, Montserrat V, Mujico JR, Loh KL, Beringer DX, van Lummel M, Thompson A, Mearin ML, Schweizer J, Kooy-Winkelaar Y, van Bergen J, Drijfhout JW, Kan WT, La Gruta NL, Anderson RP, Reid HH, Koning F, Rossjohn J. Petersen J, et al. Among authors: loh kl. Nat Struct Mol Biol. 2014 May;21(5):480-8. doi: 10.1038/nsmb.2817. Epub 2014 Apr 28. Nat Struct Mol Biol. 2014. PMID: 24777060
T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex.
Beringer DX, Kleijwegt FS, Wiede F, van der Slik AR, Loh KL, Petersen J, Dudek NL, Duinkerken G, Laban S, Joosten A, Vivian JP, Chen Z, Uldrich AP, Godfrey DI, McCluskey J, Price DA, Radford KJ, Purcell AW, Nikolic T, Reid HH, Tiganis T, Roep BO, Rossjohn J. Beringer DX, et al. Among authors: loh kl. Nat Immunol. 2015 Nov;16(11):1153-61. doi: 10.1038/ni.3271. Epub 2015 Oct 5. Nat Immunol. 2015. PMID: 26437244
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, Coates PT, Gregersen JW, Purcell AW, Holdsworth SR, La Gruta NL, Reid HH, Rossjohn J, Kitching AR. Ooi JD, et al. Among authors: loh kl. Nature. 2017 May 11;545(7653):243-247. doi: 10.1038/nature22329. Epub 2017 May 3. Nature. 2017. PMID: 28467828 Free PMC article.
A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity.
Ooi JD, Jiang JH, Eggenhuizen PJ, Chua LL, van Timmeren M, Loh KL, O'Sullivan KM, Gan PY, Zhong Y, Tsyganov K, Shochet LR, Ryan J, Stegeman CA, Fugger L, Reid HH, Rossjohn J, Heeringa P, Holdsworth SR, Peleg AY, Kitching AR. Ooi JD, et al. Among authors: loh kl. Nat Commun. 2019 Jul 29;10(1):3392. doi: 10.1038/s41467-019-11255-0. Nat Commun. 2019. PMID: 31358739 Free PMC article.
22 results