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Sub-lingual administration of a polyvalent mechanical bacterial lysate (PMBL) in patients with moderate, severe, or very severe chronic obstructive pulmonary disease (COPD) according to the GOLD spirometric classification: A multicentre, double-blind, randomised, controlled, phase IV study (AIACE study: Advanced Immunological Approach in COPD Exacerbation).
Braido F, Melioli G, Cazzola M, Fabbri L, Blasi F, Moretta L, Canonica GW; AIACE Study Group. Braido F, et al. Among authors: melioli g. Pulm Pharmacol Ther. 2015 Aug;33:75-80. doi: 10.1016/j.pupt.2015.03.006. Epub 2015 May 5. Pulm Pharmacol Ther. 2015. PMID: 25951945 Clinical Trial.
The administration of a polyvalent mechanical bacterial lysate in elderly patients with COPD results in serological signs of an efficient immune response associated with a reduced number of acute episodes.
Ricci R, Palmero C, Bazurro G, Riccio AM, Garelli V, Di Marco E, Cirillo C, Braido F, Canonica GW, Melioli G. Ricci R, et al. Among authors: melioli g. Pulm Pharmacol Ther. 2014 Feb;27(1):109-13. doi: 10.1016/j.pupt.2013.05.006. Epub 2013 Jun 21. Pulm Pharmacol Ther. 2014. PMID: 23792312 Clinical Trial.
The bacterial lysate Lantigen B reduces the number of acute episodes in patients with recurrent infections of the respiratory tract: the results of a double blind, placebo controlled, multicenter clinical trial.
Braido F, Melioli G, Candoli P, Cavalot A, Di Gioacchino M, Ferrero V, Incorvaia C, Mereu C, Ridolo E, Rolla G, Rossi O, Savi E, Tubino L, Reggiardo G, Baiardini I, di Marco E, Rinaldi G, Canonica GW; Lantigen Study Group; Accorsi C, Bossilino C, Bonzano L, DiLizia M, Fedrighini B, Garelli V, Gerace V, Maniscalco S, Massaro I, Messi A, Milanese M, Peveri S, Penno A, Pizzimenti S, Pozzo T, Raie A, Regina S, Sclifò F. Braido F, et al. Among authors: melioli g. Immunol Lett. 2014 Dec;162(2 Pt B):185-93. doi: 10.1016/j.imlet.2014.10.026. Epub 2014 Nov 3. Immunol Lett. 2014. PMID: 25445613 Free PMC article. Clinical Trial.
May we strengthen the human natural defenses with bacterial lysates?
Villa E, Garelli V, Braido F, Melioli G, Canonica GW. Villa E, et al. Among authors: melioli g. World Allergy Organ J. 2010 Aug;3(8 Suppl):S17-23. doi: 10.1097/WOX.0b013e3181ee0cfd. World Allergy Organ J. 2010. PMID: 23282746 Free PMC article.
CD4(+)CD25(high)CD127(-) regulatory T-cells in COPD: smoke and drugs effect.
Chiappori A, Folli C, Balbi F, Caci E, Riccio AM, De Ferrari L, Melioli G, Braido F, Canonica GW. Chiappori A, et al. Among authors: melioli g. World Allergy Organ J. 2016 Feb 12;9:5. doi: 10.1186/s40413-016-0095-2. eCollection 2016. World Allergy Organ J. 2016. PMID: 26904157 Free PMC article.
185 results