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X-ray crystal structures of monomeric and dimeric peptide inhibitors in complex with the human neonatal Fc receptor, FcRn.
Mezo AR, Sridhar V, Badger J, Sakorafas P, Nienaber V. Mezo AR, et al. J Biol Chem. 2010 Sep 3;285(36):27694-701. doi: 10.1074/jbc.M110.120667. Epub 2010 Jun 30. J Biol Chem. 2010. PMID: 20592032 Free PMC article.
A family of peptides comprising the consensus motif GHFGGXY, where X is preferably a hydrophobic amino acid, was shown previously to inhibit the human IgG:human FcRn protein-protein interaction (Mezo, A. ...M., Kamphaus, G. D., Fraley, C., Zhang, Y., D …
A family of peptides comprising the consensus motif GHFGGXY, where X is preferably a hydrophobic amino acid, was shown previou …
Neonatal Fc receptor promotes immune complex-mediated glomerular disease.
Olaru F, Luo W, Suleiman H, St John PL, Ge L, Mezo AR, Shaw AS, Abrahamson DR, Miner JH, Borza DB. Olaru F, et al. Among authors: mezo ar. J Am Soc Nephrol. 2014 May;25(5):918-25. doi: 10.1681/ASN.2013050498. Epub 2013 Dec 19. J Am Soc Nephrol. 2014. PMID: 24357670 Free PMC article.
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