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569 results

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Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib.
Bessette DC, Tilch E, Seidens T, Quinn MC, Wiegmans AP, Shi W, Cocciardi S, McCart-Reed A, Saunus JM, Simpson PT, Grimmond SM, Lakhani SR, Khanna KK, Waddell N, Al-Ejeh F, Chenevix-Trench G. Bessette DC, et al. PLoS One. 2015 May 13;10(5):e0125232. doi: 10.1371/journal.pone.0125232. eCollection 2015. PLoS One. 2015. PMID: 25969993 Free PMC article.
Dominant negative ATM mutations in breast cancer families.
Chenevix-Trench G, Spurdle AB, Gatei M, Kelly H, Marsh A, Chen X, Donn K, Cummings M, Nyholt D, Jenkins MA, Scott C, Pupo GM, Dörk T, Bendix R, Kirk J, Tucker K, McCredie MR, Hopper JL, Sambrook J, Mann GJ, Khanna KK. Chenevix-Trench G, et al. J Natl Cancer Inst. 2002 Feb 6;94(3):205-15. doi: 10.1093/jnci/94.3.205. J Natl Cancer Inst. 2002. PMID: 11830610
Genetic and histopathologic evaluation of BRCA1 and BRCA2 DNA sequence variants of unknown clinical significance.
Chenevix-Trench G, Healey S, Lakhani S, Waring P, Cummings M, Brinkworth R, Deffenbaugh AM, Burbidge LA, Pruss D, Judkins T, Scholl T, Bekessy A, Marsh A, Lovelock P, Wong M, Tesoriero A, Renard H, Southey M, Hopper JL, Yannoukakos K, Brown M, Easton D, Tavtigian SV, Goldgar D, Spurdle AB; kConFab Investigators. Chenevix-Trench G, et al. Cancer Res. 2006 Feb 15;66(4):2019-27. doi: 10.1158/0008-5472.CAN-05-3546. Cancer Res. 2006. PMID: 16489001
Characterization of the breast cancer associated ATM 7271T>G (V2424G) mutation by gene expression profiling.
Waddell N, Jonnalagadda J, Marsh A, Grist S, Jenkins M, Hobson K, Taylor M, Lindeman GJ, Tavtigian SV, Suthers G, Goldgar D, Oefner PJ; kConFab Investigators; Taylor D, Grimmond S, Khanna KK, Chenevix-Trench G. Waddell N, et al. Genes Chromosomes Cancer. 2006 Dec;45(12):1169-81. doi: 10.1002/gcc.20381. Genes Chromosomes Cancer. 2006. PMID: 17001622
Mutation analysis of five candidate genes in familial breast cancer.
Marsh A, Healey S, Lewis A, Spurdle AB, Kedda MA, Khanna KK; kConFab; Mann GJ, Pupo GM, Lakhani SR, Chenevix-Trench G. Marsh A, et al. Breast Cancer Res Treat. 2007 Nov;105(3):377-89. doi: 10.1007/s10549-006-9461-z. Epub 2006 Dec 23. Breast Cancer Res Treat. 2007. PMID: 17187232
A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP.
Pagan JK, Arnold J, Hanchard KJ, Kumar R, Bruno T, Jones MJ, Richard DJ, Forrest A, Spurdle A, Verdin E, Crossley M, Fanciulli M, Chenevix-Trench G, Young DB, Khanna KK. Pagan JK, et al. J Biol Chem. 2007 May 18;282(20):15248-57. doi: 10.1074/jbc.M700246200. Epub 2007 Mar 22. J Biol Chem. 2007. PMID: 17379597 Free article.
BCoR-L1 variation and breast cancer.
Lose F, Arnold J, Young DB, Brown CJ, Mann GJ, Pupo GM; Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer; Khanna KK, Chenevix-Trench G, Spurdle AB. Lose F, et al. Breast Cancer Res. 2007;9(4):R54. doi: 10.1186/bcr1759. Breast Cancer Res. 2007. PMID: 17697391 Free PMC article.
569 results