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Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys.
Hoyt SB, Park MK, London C, Xiong Y, Tata J, Bennett DJ, Cooke A, Cai J, Carswell E, Robinson J, MacLean J, Brown L, Belshaw S, Clarkson TR, Liu K, Liang GB, Struthers M, Cully D, Wisniewski T, Ren N, Bopp C, Sok A, Cai TQ, Stribling S, Pai LY, Ma X, Metzger J, Verras A, McMasters D, Chen Q, Tung E, Tang W, Salituro G, Buist N, Kuethe J, Rivera N, Clemas J, Zhou G, Gibson J, Maxwell CA, Lassman M, McLaughlin T, Castro-Perez J, Szeto D, Forrest G, Hajdu R, Rosenbach M, Ali A. Hoyt SB, et al. Among authors: rivera n. ACS Med Chem Lett. 2015 Apr 7;6(5):573-8. doi: 10.1021/acsmedchemlett.5b00054. eCollection 2015 May 14. ACS Med Chem Lett. 2015. PMID: 26005536 Free PMC article.
Iron-catalysed tritiation of pharmaceuticals.
Yu RP, Hesk D, Rivera N, Pelczer I, Chirik PJ. Yu RP, et al. Among authors: rivera n. Nature. 2016 Jan 14;529(7585):195-9. doi: 10.1038/nature16464. Nature. 2016. PMID: 26762456
Highly regioselective Friedländer reaction.
Hsiao Y, Rivera NR, Yasuda N, Hughes DL, Reider PJ. Hsiao Y, et al. Among authors: rivera nr. Org Lett. 2001 Apr 19;3(8):1101-3. doi: 10.1021/ol006785v. Org Lett. 2001. PMID: 11348169
A concise synthesis of a β-lactamase inhibitor.
Mangion IK, Ruck RT, Rivera N, Huffman MA, Shevlin M. Mangion IK, et al. Among authors: rivera n. Org Lett. 2011 Oct 21;13(20):5480-3. doi: 10.1021/ol202195n. Epub 2011 Sep 15. Org Lett. 2011. PMID: 21916523
285 results