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Regulation of SIRT1 protein levels by nutrient availability.
Kanfi Y, Peshti V, Gozlan YM, Rathaus M, Gil R, Cohen HY. Kanfi Y, et al. Among authors: cohen hy. FEBS Lett. 2008 Jul 9;582(16):2417-23. doi: 10.1016/j.febslet.2008.06.005. Epub 2008 Jun 9. FEBS Lett. 2008. PMID: 18544345 Free article.
The sirtuin SIRT6 regulates lifespan in male mice.
Kanfi Y, Naiman S, Amir G, Peshti V, Zinman G, Nahum L, Bar-Joseph Z, Cohen HY. Kanfi Y, et al. Among authors: cohen hy. Nature. 2012 Feb 22;483(7388):218-21. doi: 10.1038/nature10815. Nature. 2012. PMID: 22367546
Characterization of physiological defects in adult SIRT6-/- mice.
Peshti V, Obolensky A, Nahum L, Kanfi Y, Rathaus M, Avraham M, Tinman S, Alt FW, Banin E, Cohen HY. Peshti V, et al. Among authors: cohen hy. PLoS One. 2017 Apr 27;12(4):e0176371. doi: 10.1371/journal.pone.0176371. eCollection 2017. PLoS One. 2017. PMID: 28448551 Free PMC article.
SIRT6 exhibits nucleosome-dependent deacetylase activity.
Gil R, Barth S, Kanfi Y, Cohen HY. Gil R, et al. Among authors: cohen hy. Nucleic Acids Res. 2013 Oct;41(18):8537-45. doi: 10.1093/nar/gkt642. Epub 2013 Jul 26. Nucleic Acids Res. 2013. PMID: 23892288 Free PMC article.
Restoration of energy homeostasis by SIRT6 extends healthy lifespan.
Roichman A, Elhanati S, Aon MA, Abramovich I, Di Francesco A, Shahar Y, Avivi MY, Shurgi M, Rubinstein A, Wiesner Y, Shuchami A, Petrover Z, Lebenthal-Loinger I, Yaron O, Lyashkov A, Ubaida-Mohien C, Kanfi Y, Lerrer B, Fernández-Marcos PJ, Serrano M, Gottlieb E, de Cabo R, Cohen HY. Roichman A, et al. Among authors: cohen hy. Nat Commun. 2021 May 28;12(1):3208. doi: 10.1038/s41467-021-23545-7. Nat Commun. 2021. PMID: 34050173 Free PMC article.
It is a branched road to adipose tissue aging.
Touitou N, Lerrer B, Cohen HY. Touitou N, et al. Among authors: cohen hy. Nat Aging. 2023 Aug;3(8):911-912. doi: 10.1038/s43587-023-00456-4. Nat Aging. 2023. PMID: 37488414 No abstract available.
51 results