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Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci†.
Kirsten H, Al-Hasani H, Holdt L, Gross A, Beutner F, Krohn K, Horn K, Ahnert P, Burkhardt R, Reiche K, Hackermüller J, Löffler M, Teupser D, Thiery J, Scholz M. Kirsten H, et al. Among authors: loffler m. Hum Mol Genet. 2015 Aug 15;24(16):4746-63. doi: 10.1093/hmg/ddv194. Epub 2015 May 27. Hum Mol Genet. 2015. PMID: 26019233 Free PMC article. Clinical Trial.
Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.
Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP. Rosendahl J, et al. Among authors: loffler m. Gut. 2018 Oct;67(10):1855-1863. doi: 10.1136/gutjnl-2017-314454. Epub 2017 Jul 28. Gut. 2018. PMID: 28754779 Free PMC article.
Association of plasma trimethylamine N-oxide levels with atherosclerotic cardiovascular disease and factors of the metabolic syndrome.
Ringel C, Dittrich J, Gaudl A, Schellong P, Beuchel CF, Baber R, Beutner F, Teren A, Engel C, Wirkner K, Thiele H, Büttner P, Löffler M, Scholz M, Thiery J, Ceglarek U. Ringel C, et al. Among authors: loffler m. Atherosclerosis. 2021 Oct;335:62-67. doi: 10.1016/j.atherosclerosis.2021.09.026. Epub 2021 Sep 23. Atherosclerosis. 2021. PMID: 34583200
DNA methylation patterns reflect individual's lifestyle independent of obesity.
Klemp I, Hoffmann A, Müller L, Hagemann T, Horn K, Rohde-Zimmermann K, Tönjes A, Thiery J, Löffler M, Burkhardt R, Böttcher Y, Stumvoll M, Blüher M, Krohn K, Scholz M, Baber R, Franks PW, Kovacs P, Keller M. Klemp I, et al. Among authors: loffler m. Clin Transl Med. 2022 Jun;12(6):e851. doi: 10.1002/ctm2.851. Clin Transl Med. 2022. PMID: 35692099 Free PMC article.
Simultaneous Mass Spectrometry-Based Apolipoprotein Profiling and Apolipoprotein E Phenotyping in Patients with ASCVD and Mild Cognitive Impairment.
Begcevic Brkovic I, Zöhrer B, Scholz M, Reinicke M, Dittrich J, Kamalsada S, Baber R, Beutner F, Teren A, Engel C, Wirkner K, Thiele H, Löffler M, Riedel-Heller SG, Ceglarek U. Begcevic Brkovic I, et al. Among authors: loffler m. Nutrients. 2022 Jun 15;14(12):2474. doi: 10.3390/nu14122474. Nutrients. 2022. PMID: 35745204 Free PMC article.
475 results